Long-Term Follow-up of Full-Awake Hand Surgery in Major Flexor Tendon Injury of the Hand and Forearm

Conclusions Full-awake hand surgery is potential surgical approach for major flexor tendon trauma cases resulting in satisfactory long term functional outcome.
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Hand Surgery Source Type: research

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Hongfei Gu1†, Shuang Shao2†, Jie Liu3,4,5, Zhenqian Fan2, Yu Chen2, Jingxian Ni3,4,5, Conglin Wang6, Jun Tu3,4,5, Xianjia Ning3,4,5, Yongzhong Lou1*, Bin Li1* and Jinghua Wang3,4,5* 1Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China 2Department of Endocrinology and Metabolism, The Second Hospital of Tianjin Medical University, Tianjin, China 3Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China 4Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, China 5Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration i...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
In this study, the cerebral-protective effect of crocin was evaluated on a rat transient middle cerebral artery occlusion (MCAO) model. Our data showed that oral administration of crocin had better effectiveness in cerebral protection than an intravenous injection. Neither crocin nor its metabolite crocetin were determined in the brain of cerebral I/R rats, indicating a target site of periphery. Abundant crocetin was detected in plasma after oral administration instead of intravenous injection of crocin. Meanwhile, orally administered crocetin showed similar cerebral protection to that of crocin, but this exciting effect w...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. The low certainty of evidence downgrades our confidence in making recommendations to clinical practice. Introduction Shoulder-hand syndrome (SHS) is a common condition among people who have had a stroke, with its reported prevalence ranging from 12% to 49% (1, 2). The main symptoms of SHS include pain, hyperalgesia, joint swelling and limitations in range of motion (ROM) (3). Post-stroke SHS is also named type I complex ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion The high prevalence of comorbidities in patients with stroke indicates the need for therapies in preclinical studies that take into account these comorbidities in order to avoid failures in translation to the patient. Preclinical studies are beginning to evaluate the efficacy of MSC treatment in stroke associated with comorbidities, especially hypertension, for ischemic and hemorrhagic stroke. Regarding aging and diabetes, only ischemic stroke studies have been performed. For the moment, few studies have been performed and contradictory results are being reported. These contradictory results may be due to the u...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Myelomeningocele (MMC), the most severe form of spina bifida, occurs in approximately 1 in 1000 –2000 births and is associated with significant disability and morbidity.1 A randomized trial published on 2011 (the MOMS trial) changed clinical practice by showing that open fetal surgery of MMC, conducted between 19 and 26 weeks’ gestation, improved a number of important outcomes, but was a ssociated with maternal and fetal risks.2 Prenatal repair decreased the rate of death or the need for a shunt at 12 months of age, decreased the rate of hindbrain herniation, doubled the rate of the ability to walk independ...
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Tags: Correspondence Source Type: research
Myelomeningocele (MMC), the most severe form of spina bifida, occurs in approximately 1 in 1000-2000 births and is associated with significant disability and morbidity.1 A randomized trial published on 2011 (the MOMS trial) changed clinical practice by showing that open fetal surgery of MMC, conducted between 19 and 26 weeks ’ gestation, improved a number of important outcomes, but was associated with maternal and fetal risks.2 Prenatal repair decreased the rate of death or the need for a shunt at 12 months of age, decreased the rate of hindbrain herniation, doubled the rate of the ability to walk independently, and ...
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Source Type: research
ORHub is a HIPAA compliant, physician-driven digital software company focused on improving profitability and the cost effectiveness of hospitals through real-time smart data and analytics. ORHub provides a cloud-based software solution that captures ...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Informatics Medicine Public Health Society Source Type: blogs
ConclusionThe presented missions contribute significantly to an improvement in local healthcare and decrease the burden of disease. We were able to show the sustainable character of these surgical missions. As a next step, we will analyse the cost-effectiveness of MSTs.
Source: Hernia - Category: Sports Medicine Source Type: research
Purpose of review Minimally invasive interventional procedures are increasingly popular options for patients who are high-risk candidates for open surgical procedures. It is unclear how to proceed in the rare circumstance of a complication during an interventional procedure, where addressing the complication would require exposing the patient to the full risk that was being avoided with the minimally invasive technique. This review provides recommendations on how to approach this paradoxical scenario. Recent findings Risk stratification, communication frameworks, and advanced care planning can facilitate shared decisi...
Source: Current Opinion in Anaesthesiology - Category: Anesthesiology Tags: ETHICS, ECONOMICS AND OUTCOME: Edited by Stanley H. Rosenbaum Source Type: research
Conclusions: These results suggest that strain-specific changes in chromatin and transcription in response to chemical exposure lead to a “compensation” for underlying genetic-driven interindividual differences in the baseline chromatin and transcriptional state. This work represents an example of how chemical and environmental exposures can be evaluated to better understand gene-by-environment interactions, and it demonstrates the important role of chromatin response in transcriptomic changes and, potentially, in deleterious effects of exposure. https://doi.org/10.1289/EHP1937 Received: 21 March 2017 Revis...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
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