Potential Antimicrobial Applications of Chitosan Nanoparticles (ChNP).

Potential Antimicrobial Applications of Chitosan Nanoparticles (ChNP). J Microbiol Biotechnol. 2019 Jul 10;: Authors: Rozman NAS, Tong WY, Leong CR, Tan WN, Hasanolbasori MA, Abdullah SZ Abstract Polymeric nanoparticles are widely used for drug delivery due to its biodegradability property. Among the wide array of polymer, chitosan has received growing interest among researchers. It was widely used as a vehicle in polymeric nanoparticles for drug targeting. This review explored the current research on the antimicrobial activity of chitosan nanoparticles (ChNP) and the impact on the clinical applications. The antimicrobial activities of ChNP were widely reported against bacteria, fungi, yeasts and algae, on both in vivo and in vitro studies. For pharmaceutical applications, ChNP was used as antimicrobial coating for promoting wound healing, prevent infections and combat the rise of infectious disease. Besides, ChNP also exhibited significant inhibitory on food borne microorganisms, particularly on fruits and vegetables. It is noteworthy that ChNP can be also applied to deliver antimicrobial drug, which further enhance the efficiency and stability of the antimicrobial agent. The present review addresses the potential antimicrobial applications of ChNP from these few aspects. PMID: 31288302 [PubMed - as supplied by publisher]
Source: Journal of Microbiology and Biotechnology - Category: Biotechnology Authors: Tags: J Microbiol Biotechnol Source Type: research