How to ease arthritis: Evidence suggests this popular fruit could keep flare-ups in check
Arthritis is a common condition in the UK, affecting more than 10 million people. While there is no cure, certain products have been proven to alleviate symptoms. Growing evidence suggests this popular fruit could help.
In conclusion, modulation of miR‑145‑5p expression is potentially useful for the treatment of RA inflammation, by regulating the expression of MMPs, and MMP‑9 in particular, through inhibition of the NF‑κB pathway. PMID: 31322192 [PubMed - as supplied by publisher]
Conclusions: The improvements in PsA related functional impairment could lead to sizable productivity effects within the economy. PMID: 31322444 [PubMed - as supplied by publisher]
CONCLUSION: Tofacitinib did not require dose modification or restrictions for age, body weight, sex, race, ethnicity, or baseline disease severity in patients with active PsA based on the magnitude of exposure relative to a reference patient. Dosing adjustments for renal impairment were derived from a separate phase 1 study. . PMID: 31319908 [PubMed - as supplied by publisher]
Conclusion. EA on ST36 and GB39 acupoints can effectively inhibit synovial angiogenesis in the AA rat model via downregulating HIF-1α/VEGF expression. PMID: 31316573 [PubMed]
CONCLUSIONS This study suggested that the TT genotype and T allele in rs17221959 decreased RA risk. Smoking could decrease the protective effect of TT. PMID: 31316048 [PubMed - in process]
Knee pain due to arthritis or injury is the second most common cause of chronic pain in the United States. Osteoarthritis affects more than 30 million adults in the United States. And the rate of anterior cruciate ligament (ACL) tears among children and teens has been increasing about 2.3% per year for the past two decades, according to a new study. The specific cause of a patientâs knee pain has always been difficult to determine because diagnostic tools such as x-ray or MRI only image the joint in a static standing or lying down position, not in motion when the patient is feeling pain. â...
Authors: Dalal A PMID: 31315345 [PubMed - in process]
Authors: Jagdish RK, Shailly, Bhatnagar MK PMID: 31315331 [PubMed - in process]
AbstractObjectivesTo develop and evaluate an illustrated, stand-alone, interactive evidence-based shared decision making (SDM) aid for JIA children; its ability to produce positive perceived involvement of JIA patients in their own management and its impact on their adherence to therapy, school absenteeism and treatment outcomes.MethodsThe SDM aid was developed to offer information about the disease, risks and benefits of treatment. A multidisciplinary team defined SDM criteria based on international standards (IPDAS). Eight categories emerged as highly important for SDM. Each category was supported by simple illustrations...
Conclusions: These findings demonstrate that: 1) TNF-Tg mice display a restrictive pathology, and 2) in vivo µCT is a valid outcome measure to infer changes in pulmonary mechanical and functional parameters. PMID: 31318607 [PubMed - as supplied by publisher]