Pineal gland dysfunction in Alzheimer ’s disease: relationship with the immune-pineal axis, sleep disturbance, and neurogenesis

Alzheimer ’s disease (AD) is a globally common neurodegenerative disease, which is accompanied by alterations to various lifestyle patterns, such as sleep disturbance. The pineal gland is the primary endocrine ...
Source: Molecular Neurodegeneration - Category: Neurology Authors: Tags: Review Source Type: research

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On average, family members spend nearly 22 hours each week caring for parents, grandparents and siblings with Alzheimer's and other conditions. But a new intervention may give them back some of those lost sleep hours.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
DISCUSSION: WPNs are extremely vulnerable to AD but not to 4 repeat tauopathies. Considering that WPNs are involved early in AD, such degeneration should be included in the models explaining sleep-wake disturbances in AD and considered when designing a clinical intervention. Sparing of WPNs in PSP, a condition featuring hyperinsomnia, suggest that interventions to suppress the arousal system may benefit patients with PSP. PMID: 31416793 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
DiscussionWPNs are extremely vulnerable to AD but not to 4 repeat tauopathies. Considering that WPNs are involved early in AD, such degeneration should be included in the models explaining sleep-wake disturbances in AD and considered when designing a clinical intervention. Sparing of WPNs in PSP, a condition featuring hyperinsomnia, suggest that interventions to suppress the arousal system may benefit patients with PSP.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Previously, it was unclear if disturbed sleep put people at risk of Alzheimer's - or if disease-related brain changes lead to it. A new study by UCSF shows dementia crushes brain cells that keep us awake.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Sleep patterns often run in families, and researchers have been identifying genes that influence them.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Sleep Genetics and Heredity Biorhythms Alzheimer ' s Disease Source Type: news
Initial results from a feasibility study conducted by Eli Lilly and Company (NYSE: LLY), Evidation Health, and Apple Inc. (NASDAQ: AAPL) showed that an iPhone, Apple Watch, iPad and the Beddit sleep monitoring device, in combination with digital apps may be able to differentiate people with mild cognitive impairment (MCI) and mild Alzheimer's disease dementia.
Source: World Pharma News - Category: Pharmaceuticals Tags: Featured Eli Lilly and Company Business and Industry Source Type: news
Initial results from a feasibility study conducted by Eli Lilly and Company (NYSE: LLY), Evidation Health, and Apple Inc. (NASDAQ: AAPL) showed that an iPhone, Apple Watch, iPad and the Beddit sleep monitoring device, in combination with digital apps may be able to differentiate people with mild cognitive impairment (MCI) and mild Alzheimer's disease dementia.
Source: eHealth News EU - Category: Information Technology Tags: Featured Industry Business and Industry Source Type: news
Gradual memory loss, cognitive decline, wandering off to unknown places, being unable to dress in the morning: to live with dementia and Alzheimer’s disease might be a heart-wrenching burden for both patients and their loved ones. As the global population ages, and the number of individuals suffering from these conditions rises, digital technologies must step forward and offer some solutions for early detection and disease management. That’s what we examined in detail here, so let’s see the intersections of digital health and Alzheimer’s disease. Have you seen Aurora Borealis? Your mind can pl...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine alzheimer Alzheimer's disease brain cognitive health dementia digital digital health elderly elderly care Healthcare Innovation medical technology Source Type: blogs
Conditions:   Alzheimer Disease;   Sleep Interventions:   Other: Multimodal brain imaging (MRI);   Other: Actimetry;   Other: Sleep Diary Sponsor:   University Hospital, Bordeaux Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
What Color is Monday? This video on synesthesia is one of the Top Ten videos in the Society for NeuroscienceBrain Awareness Video Contest. Voting for the 2019 People's Choice Award closes 12 p.m. Eastern time on August 30, 2019.However, it wasn't immediately apparent to me how you're supposed to cast your vote...The entire playlist ison YouTube. 1  4:09Now playing Multitasking2 4:43Now playing How Ketamine Treats Depression3 4:40Now playing Procrastination: I'll Think of a Title Later4 3:55Now playing Seeing Culture in Our Brain5 3:58Now playing Theory of Mind6 4:00Now playing How Neu...
Source: The Neurocritic - Category: Neuroscience Authors: Source Type: blogs
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