Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir1.

Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir1. Emerg Infect Dis. 2019 Oct 17;25(10): Authors: Mishin VP, Patel MC, Chesnokov A, De La Cruz J, Nguyen HT, Lollis L, Hodges E, Jang Y, Barnes J, Uyeki T, Davis CT, Wentworth DE, Gubareva LV Abstract Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors. PMID: 31287050 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31287050?dopt=Abstract

Source: Emerging Infectious Diseases - July 11, 2019 Category: Infectious Diseases Authors: Mishin VP, Patel MC, Chesnokov A, De La Cruz J, Nguyen HT, Lollis L, Hodges E, Jang Y, Barnes J, Uyeki T, Davis CT, Wentworth DE, Gubareva LV Tags: Emerg Infect Dis Source Type: research