Molecular diagnosis in house dust mite allergic patients suggests clinical relevance of Der p 23 in asthmatic children.

CONCLUSIONS: Most of our population with mite allergy is sensitized to Der p 1, Der p 2 and Der p 23 major allergens; however, 5% were sensitized only to Der p 23 of the allergens evaluated. Sensitization to Der p 23 should be considered in the diagnosis and treatment of mite allergy, especially in patients with moderate and severe asthma because it may worsen the clinical phenotype.
PMID: 31283524 [PubMed - as supplied by publisher]

Source: Journal of Investigational Allergology and Clinical Immunology - July 7, 2019 Category: Allergy & Immunology Authors: Jiménez-Feijoo R, Pascal M, Moya R, Riggioni C, Domínguez O, Lózano J, Álvaro-Lozano M, Piquert M, Machinena A, Folque M, Dias M, Carnés J, Plaza AM Tags: J Investig Allergol Clin Immunol Source Type: research