Predictors of Adverse Events Following Cleft Palate Repair

Conclusions: Although adverse events following cleft palate surgery are rare, systemic disease remains the greatest predictor for readmission and reoperation. Neurologic and pulmonary diseases are the greatest systemic risk factors. Intraoperative adverse events requiring blood transfusion are the greatest surgical risk factor for post-surgical complications.
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Original Articles Source Type: research

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Abstract Retrospective analysis has already shown correlation between severe Chronic Periodontitis (CP) cases with human papiloma virus (HPV). Hence, we aimed to explore deep-seated infected granulation tissue removed during periodontal flap surgery procedures for residential bacterial species between HPV+ and HVP- CP cases, which may serve as good predisposition marker for oral cancer. All CP-granulation samples showed the prominence of Firmicutes, Proteobacteria, and Bacteroidetes phyla with an abundance of gram negative anaerobes, except Streptococcus. In Beta diversity nonmetric multidimensional scaling plot, ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Authors: Zhang Y, Li L, Xu Y, Zhao X, Li F Abstract The regeneration of the skin is vital to our wound healing and skin repair abilities. Adult epidermal stem cells (ESCs) have been shown to have the potential to renew old and dead skin cells, and ESCs have been implemented in stem cell-based therapies. GPR30 is a G protein-coupled membrane receptor for oestrogen, which has been shown to regulate cell proliferation and programmed cell death. Here, we examined the biological function of GPR30 in isolated adult murine ESCs. We show that GPR30 is fairly expressed in ESCs and is repressed upon ultraviolet B (UV-B) trea...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Source: BMJ News - Category: General Medicine Source Type: research
ConclusionsThe ability of AVATAR to obviate the need for daily anesthesia in pediatric RT provides substantial cost-savings. These findings argue for increased utilization of AVATAR and for analyses of RT targeting the accuracy of AVATAR versus conventional anesthesia-guided treatment of pediatric malignancies.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
Authors: PMID: 31713238 [PubMed]
Source: Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Tags: Clin Pharmacol Ther Source Type: research
Publication date: Available online 13 November 2019Source: Journal of Materials Research and TechnologyAuthor(s): Inamara Amanda Souza Santos, Vanessa Rodrigues de Medeiros Santos, Willian dos Reis Lima, Aline Lima da Silva, Breno Totti Maia, José Roberto de OliveiraAbstractThe successful application of the repair and prevention of LD converters refractories technique called Slag Splashing requires a close control of the slag physicochemical properties (basicity, viscosity and surface tension), as well as suitable selection of operational parameters and geometric configurations. In this paper, a Slag Splashing proce...
Source: Journal of Materials Research and Technology - Category: Materials Science Source Type: research
Publication date: Available online 12 November 2019Source: NeuroImageAuthor(s): Jaakko Paasonen, Hanne Laakso, Tiina Pirttimäki, Petteri Stenroos, Raimo A. Salo, Ekaterina Zhurakovskaya, Lauri J. Lehto, Heikki Tanila, Michael Garwood, Shalom Michaeli, Djaudat Idiyatullin, Silvia Mangia, Olli GröhnAbstractFunctional magnetic resonance imaging (fMRI) studies in animal models provide invaluable information regarding normal and abnormal brain function, especially when combined with complementary stimulation and recording techniques. The echo planar imaging (EPI) pulse sequence is the most common choice for fMRI inves...
Source: NeuroImage - Category: Neuroscience Source Type: research
ConclusionWe demonstrated newly developed MSI-NGS with MSIcall accurately determines the MSI status of FFPE tumor tissues thorough sequencing of tumor samples alone without patient-matched normal controls. This approach could be applied to all types of solid tumors to determine responders to immune-oncology therapy.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
AbstractImmunotherapy has been recently approved for gastric (GC) and gastroesophageal-junction adenocarcinomas (GEC), and PD-L1 immunohistochemical evaluation represents a promising predictive biomarker in this oncological setting. A series of 125 gastroesophageal dysplastic lesions (52 low-grade, 73 high-grade) was investigated for PD-L1 and DNA mismatch repair proteins status. PD-L1 was positive (combined positive score (CPS)  ≥ 1) in 48 (31.0%) dysplastic lesions. A higher prevalence of PD-L1–positive cases was observed among esophageal specimens compared with gastric ones (p = 0.00...
Source: Virchows Archiv - Category: Pathology Source Type: research
Conclusion: In newborns with large and persistent unesthetic cephalohematoma, puncture under local anesthesia with oral sucrose can be safely proposed between day 15 and day 30 after birth.What is Known:•Infant cephalohematoma is a frequent pathology of newborns, consisting of a traumatic subperiosteal hematoma of the skull. Most cephalohematomas are small and require no treatment because they spontaneously disappear within the first month.•Large and non-resorptive cephalohematomas may have significant esthetic and functional consequences.What is New:•Early puncture under local anesthesia is a safe, effectiv...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
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