Myeloid zinc finger-1 regulates expression of cancer-associated fibroblast and cancer stemness profiles in breast cancer

Osteopontin acts thru myeloid zinc finger-1 and transforming growth factor- β to drive the adoption of a cancer-associated fibroblast phenotype by local mesenchymal stem cells. Cancer-associated fibroblasts increase cancer cell stemness.
Source: Surgery - Category: Surgery Authors: Source Type: research