Experimental Ebola Treatments Look Successful in Lab Studies, Says the CDC

A humanitarian crisis, attacks on health workers and rampant misinformation have for months fueled an Ebola outbreak in the Democratic Republic of the Congo (DRC), amplifying the effects of a highly contagious and often-fatal disease. As a result, international health groups have declared this the second-worst Ebola outbreak in history, with more than 1,500 people dying since it started in August 2018. New research from the U.S. Centers for Disease Control and Prevention (CDC) offers some hope, highlighting two treatments that could help bring the deadly outbreak under control. The study, published in the Lancet Infectious Diseases, finds that two experimental Ebola treatments—Gilead Sciences’ antiviral drug remdesivir, and antibodies included in a Mapp Biopharmaceutical cocktail known as ZMapp—were shown in a lab to slow the viral strain found in the DRC, potentially offering an effective treatment to those who become infected with the hemorrhagic fever. There is no known cure for Ebola. There are some treatments available, but all were “developed to fight Ebola viruses from previous outbreaks,” lead study author and CDC microbiologist Laura McMullan said in a statement. “It’s vitally important to make sure existing treatments work against the virus that’s making people sick now.” CDC researchers isolated and recreated the specific viral strain circulating in the DRC, which is known as the Ituri strain, and studied its a...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease Source Type: news

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Last year, when I visited the town of Beni, in the Democratic Republic of the Congo (DRC), people did not shake hands. Bottles of disinfectant and buckets of chlorinated water were at the entrance of every business. Misinformation spread across social networks and on news-sites, and treatment centers in the northeastern province of North Kivu were being attacked by armed militias. At the time, Beni was one of the centers of a devastating Ebola outbreak, the second most deadly in world history. According to the World Health Organization, almost 3,500 people were sickened by the virus, and more than 2,000 died, a case fatali...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Credit: UNBy Ifeanyi Nsofor and Adaeze OrehABUJA, Mar 30 2020 (IPS) As COVID-19 surges globally and leaves fear and panic in its wake, global efforts are underway to find a cure. Yet, the same level of response is lacking for several other infectious diseases that kill millions annually. These kinds of neglected tropical diseases (NTDs) are a broad group of communicable diseases which affect more than two billion people and cost developing economies billions of dollars every year. Lassa Fever is an example and is endemic in Nigeria and other West African countries such as Benin, Ghana, Guinea, Liberia, ...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health TerraViva United Nations Neglected Tropical Diseases (NTDs) Source Type: news
The recent WHO decision to declare the novel coronavirus outbreak a Public Health Emergency of International Concern (PHEIC), while both appropriate and hardly surprising, offers the opportunity to reflect on the previous PHEIC which was declared, namely the Ebola epidemic in Kivu region, Democratic Republic of the Congo (DRC). And you should really say the ongoing Ebola epidemic, as during the time since the declaration in July 2019 through to the present day (March 2020), a total of 3,453 cases have been reported [1]. The nCoV-2019 outbreak is still ballooning; as of today, over 400,000 confirmed cases worldwide with no ...
Source: GIDEON blog - Category: Databases & Libraries Authors: Tags: Ebooks Epidemiology Outbreaks Source Type: blogs
Dr. Bruce Aylward has almost 30 years experience in fighting polio, Ebola and other diseases, and now, he’s turned his attention to stopping the spread of COVID-19. Aylward, the senior adviser to the Director-General of the World Health Organization (WHO), is one of the world’s top officials in charge of fighting the coronavirus pandemic. The doctor, who led a joint WHO mission to China in February to study the effectiveness of the coronavirus response in the country, has seen firsthand the measures Beijing took to fight the virus. Now he’s sharing what he learned with governments and communicating with t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 overnight Source Type: news
Dr. Bruce Aylward has almost 30 years experience in fighting polio, Ebola and other diseases, and now, he’s turned his attention to stopping the spread of COVID-19. Aylward, the senior adviser to the Director-General of the World Health Organization (WHO), is one of the world’s top officials in charge of fighting the coronavirus pandemic. The doctor, who lead a joint WHO mission to China in February to study the effectiveness of the coronavirus response in the country, has seen firsthand the measures Beijing took to fight the virus. Now he’s sharing what he learned with governments and communicating with ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 overnight Source Type: news
Researchers hope to conduct animal tests next week and safety trials as early as next monthCoronavirus – latest updatesSee all our coronavirus coverageA massive effort is under way to develop a UK vaccine for coronavirus within months and make it available to save lives before the end of the year, the Guardian has learned.Researchers at Oxford University, led by Prof Sarah Gilbert, are planning a safety trial on humans of what is expected to be the UK ’s first coronavirus vaccine next month. Provided that it goes smoothly, they will move directly into a larger trial to assess how effective the vaccine is at pro...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Health Coronavirus outbreak Vaccines and immunisation Medical research Science Infectious diseases UK news Ebola Source Type: news
The World Health Organization’s Emergency Use Listing (EUL) provides an approach for assessing medicines, vaccines, and diagnostics that could help address an outbreak classified by the WHO as a Public Health Emergency of International Concern (PHEIC). Robyn Meurant, executive director, regulatory services, IVDs and medical devices for NSF International, describes the EUL as “akin to the U.S. FDA’s Emergency Use Authorization” and says it could help countries that are “without great means to do testing.” ...
Source: MDDI - Category: Medical Devices Authors: Tags: Regulatory and Compliance Source Type: news
President Donald Trump’s declaration of a national emergency is designed to speed federal support to parts of America that are struggling to prepare for a coming surge of COVID-19 cases, unlocking $50 billion in aid, giving hospitals and doctors more freedom to handle a potential tsunami of sick patients and scrambling to make tests available. In a Rose Garden press conference Friday, Trump presented the emergency measures as proof that, “No nation is more prepared or more equipped to face down this crisis.” But for epidemiologists, medical experts and current and former U.S. public health officials, the ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
NEW BRUNSWICK, N.J., March 13, 2020 – Johnson &Johnson today announced that its Janssen Pharmaceutical Companies have entered a collaboration with the Beth Israel Deaconess Medical Center (BIDMC) to support the development of a preventive vaccine candidate for COVID-19. The parties have commenced preclinical testing of multiple vaccine prospects, with the aim to identify by the end of the month a COVID-19 vaccine candidate for clinical trials.Janssen is optimistic that, in collaboration with multiple global strategic partners, it can initiate a Phase 1 clinical study of a potential vaccine candidate by the end of...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Our Company Source Type: news
ConclusionsChina has started to emphasize the importance of medical product innovation as one of the solutions for tackling emerging infectious diseases. Continuing research on the development of regulatory and market incentives, as well as a multilateral collaboration mechanism that unifies cross-channel supports, would advance the process for China to enter global R&D market more effectively.
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research
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