Exposure to recurrent hypoglycemia alters hippocampal metabolism in treated streptozotocin-induced diabetic rats.
CONCLUSION: Our results demonstrate that the exposure to RH leads to metabolomics alterations in the hippocampus of insulin-treated streptozotocin-diabetic rats. Understanding how RH affects hippocampal metabolism may help attenuate the adverse effects of RH on hippocampal functions.
PMID: 31282100 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Dewan N, Shukla V, Rehni AK, Koronowski KB, Klingbeil KD, Stradecki-Cohan H, Garrett TJ, Rundek T, Perez-Pinzon MA, Dave KR Tags: CNS Neurosci Ther Source Type: research