Treatment of newly-diagnosed gastroesophageal reflux disease: a nationwide register-based cohort study.
Conclusion: Patients referred to investigation with endoscopy and diagnosed with GERD in Denmark are primarily treated with pharmacological anti-reflux treatment within the first two years with PPI being the primary agent. Only a small fraction of patients is treated surgically. PMID: 31280616 [PubMed - as supplied by publisher]
ConclusionESG is a feasible endobariatric option, but complications like gastric perforation can occur. For such complication, immediate surgical treatment is indicated.
Authors: Gomez Cifuentes J, Lopez R, Thota PN Abstract BACKGROUND: Patients with non-cardiac chest pain (NCCP) are referred for esophageal motility testing and pH monitoring since gastroesophageal reflux disease (GERD) and esophageal motility disorders are frequently encountered in these patients. Our aim was to determine the prevalence and distribution of these disorders and to identify predictors of abnormal esophageal function testing. METHODS: We performed a retrospective study of NCCP patients who presented after a negative cardiac evaluation and underwent esophageal manometry, esophageal pH monitoring and...
CONCLUSIONS: Only reflux symptoms could be attributed to sliding hiatal hernias. Hiatal hernias less than 2 cm should be considered clinically insignificant. PMID: 29616831 [PubMed - as supplied by publisher]
ConclusionCauses of abdominal pain and GERD after RYGB are difficult to identify. Gastro-gastric fistula is one of them and should be evoked when biliary reflux and abdominal pain appear.
CONCLUSION: The current study provides a novel endoscopic intervention to treat refractory GERD, which is safe, cost-effective, with no major adverse effects at one year follow up. PMID: 29488430 [PubMed - as supplied by publisher]
CONCLUSIONS: Image-enhanced endoscopic findings of vascularity and micro-erosions were very specific for non-erosive GERD. Image-enhanced endoscopy may be useful in real-time diagnosis of non-erosive GERD when patients undergo upper endoscopy for heartburn. The relative utility of image-enhanced endoscopy vs. pH-impedance monitoring, based on efficacy, cost and patient acceptance, requires additional study. PMID: 29368532 [PubMed - as supplied by publisher]
Background and aims Hiatus hernia (HH) is a key mediator of gastro-oesophageal reflux disease but little is known about its significance in the general population. We studied the structure and function of the gastro-oesophageal junction in healthy volunteers with and without HH. Methods We compared 15 volunteers with HH, detected by endoscopy or MRI scan, but without gastro-oesophageal reflux disease with 15 controls matched for age, gender and body weight. Jumbo biopsies were taken across the squamocolumnar junction (SCJ). High-resolution pH metry (12 sensors) and manometry (36 sensors) were performed upright and supine,...
CONCLUSIONS: Abnormal UES function was noted in one-third of patients with LPR or GERD. However, there were no abnormalities on esophageal function testing specific for LPR. PMID: 28471304 [PubMed - as supplied by publisher]
A 52 year-old female with a past medical history of gastroesophageal reflux and hypertension presented with a chief complaint of gradual onset substernal chest pressure and intermittent dysphagia. Cardiac evaluation of her symptoms was negative. CT scan of the chest demonstrated a mass in the posterior mediastinum which was compliant with the distal esophagus. Upper endoscopy with endoscopic ultrasound (EUS) demonstrated an anechoic cyst located between the left atrium and esophagus; the cyst was clearly associated with the esophageal wall.
Authors: Irvine AJ, Pinto-Sanchez MI, Bercik P, Moayyedi P, Ford AC Abstract OBJECTIVES: Gastro-oesophageal reflux and dyspepsia are felt to be separate upper gastrointestinal (GI) conditions. We aimed to measure the degree of overlap between them, and assess whether endoscopic findings differed. MATERIAL AND METHODS: Demographic, symptom, upper GI endoscopy and histology data were collected from consecutive adults in secondary care. Patients were categorised according to whether they reported gastro-oesophageal reflux alone, dyspepsia alone or both, and patient demographics and endoscopic findings were compare...