Synthesis and Assessment of 3-Substituted Phenazines as Novel Antichlamydial Agents.

CONCLUSION: Our findings suggested that 3-substituted phenazine derivatives might be a promising class of therapeutic agents for chlamydial infections. More effective phenazines with low toxicity could be acquired through futher chemical modification on C-3 position rather than C-4 position of phenazine.
PMID: 31284867 [PubMed - as supplied by publisher]

Source: Medicinal Chemistry - July 7, 2019 Category: Chemistry Authors: Bao X, Liu Z, Ni M, Xia C, Xu S, Yang S, Zhao Y Tags: Med Chem Source Type: research