Partitioning of radiological, stress and biochemical changes in pre-diabetic women subjected to Diabetic Yoga Protocol
ConclusionDYP reduced the HbA1C and stress levels and therefore, could be a cost-effective tool for preventing Prediabetic to Diabetic progression.
Gu et al. (AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science. 2019;363:1085–1088, https://doi.org/10.1126/science.aav1749)
Although control of chronic glycemia in the population with diabetes and end-stage renal disease (ESRD) has been extensively studied in recent years, the unique problems of short-term glycemic management in acutely ill patients undergoing dialysis have received little attention. Bally et al. evaluated the role of a “closed-loop” (glucose sensor/algorithm tablet device/insulin pump) system in a cohort of hospitalized patients with type 2 diabetes receiving hemodialysis. Compared with usual care, the intervention group had superior glycemic control without increased hypoglycemic events.
An 82-year-old male, with a history of bowel cancer with partial colectomy, gastroesophageal reflux disease, remote partial gastrectomy for peptic ulcer disease, and no documented prior kidney disease, presents with several months of fatigue and subacute decline in kidney function. He had no history of diabetes, hypertension, kidney stones, or prior urinary tract infections. He denied use of nonsteroidal anti-inflammatory agents, herbal medications, and recent antibiotics. There was no family history of renal disease.
Authors: Carretero-Anibarro E, Hamud-Uedha M PMID: 31427152 [PubMed - as supplied by publisher]
CONCLUSIONS: Dapagliflozin, in subjects with DM2, produces a medium to long-term decrease in arterial stiffness. PMID: 31420083 [PubMed - as supplied by publisher]
We read with great interest the study by O'Donnell et al,1 which investigated the risk factors of postoperative renal dysfunction after open repair of abdominal aortic aneurysm (AAA) in a large retrospective cohort.
We thank Drs Yoon and Kim for their interest in our study and the higher risk for acute kidney injury (AKI) after open repair of juxtarenal abdominal aortic aneurysms in patients taking statins preoperatively. Our understanding of the interaction between statins and postoperative renal function is constantly evolving, as both observational and randomized trials have met with mixed results. Importantly, previous studies showed that initiating statins in the perioperative period was associated with higher rates of postoperative AKI, whereas long-term statin use was associated with lower risk of renal complications.
The Wound Ischemia foot Infection (WIfI) classification has gained widespread acceptance in the vascular community as a method of categorizing disease severity in patients with chronic limb-threatening ischemia (CLTI). The original WIfI system is based on a Delphi consensus model, which relies on an iterative process of consensus amongst experts, but is not necessarily data driven. Twelve experts were selected in the formation of the initial WIfI model. The WIfI classification was initially developed in a cohort of CLTI patients not undergoing revascularization, but since then has been extrapolated to predict outcomes of m...
This study aimed to assess the impact of perioperative hemoglobin A1c (HbA1c) levels on short- and long-term results after LEB.
Macrophage (M ϕ) plasticity allows transition of Mϕs from an inflammatory to a reparative phenotype and is critical for wound healing. In pathologic conditions, such as type 2 diabetes (T2D), wounds fail to heal because of impaired resolution of inflammation. Although the mechanisms responsible for persistent T 2D inflammation are unknown, growing evidence indicates that the Toll-like receptor (TLR) 4 and saturated fatty acids (SFAs) drive Mϕ-mediated inflammation. Given the excess SFAs in T2D, we hypothesized that SFAs induce epigenetic alterations in wound Mϕs and drive Mϕ inflammation that impairs di abetic wound healing.