Colitis after checkpoint blockade: A retrospective cohort study of melanoma patients requiring admission for symptom control

ConclusionsSevere CPI ‐related GEC typically manifests within 3 months of immunotherapy exposure. Rates of second‐line immunosuppression and readmission for recrudescence were high. CTCAE grade did not capture the degree of severity in our cohort. Second‐line immunosuppression was not associated with poorer oncolo gic outcomes; however, early corticosteroid exposure was associated with decreased PFS. Further investigation is warranted.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research