Propofol attenuated TNF- α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells

The levels of tight junction proteins (TJs), especially occludin, correlate with blood-brain barrier (BBB) disruption caused by inflammation in central nervous system (CNS). It has been reported that propofol,...
Source: BMC Anesthesiology - Category: Anesthesiology Authors: Tags: Research article Source Type: research