Linoleic acid ‐derived metabolites constitute the majority of oxylipins in the rat pup brain and stimulate axonal growth in primary rat cortical neuron‐glia co‐cultures in a sex‐dependent manner

This study demonstrates that OXLAMs constitute the majority of oxylipins in the developing rat brain despite low relative abundanc e of their LA precursor, and highlights a novel role of LA and 13‐HODE in differentially influencing neuronal morphogenesis in the developing male and female brain.This article is protected by copyright. All rights reserved.

Source: Journal of Neurochemistry - July 7, 2019 Category: Neuroscience Authors: Marie Hennebelle, Rhianna K. Morgan, Sunjay Sethi, Zhichao Zhang, Hao Chen, Ana Cristina Grodzki, Pamela J. Lein, Ameer Y. Taha Tags: Original Article Source Type: research