Host Genetics, Innate Immune Responses, and Cellular Death Pathways in Poliomyelitis Patients

Conclusions: We suggest that genetic variants in innate immune defences and cell death pathways contribute to the clinical presentation of PV infection. Importantly, this study is the first to uncover the genetic profile in patients with PPM, combined with investigations of immune responses and viral burden in primary cells.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research