National Advisory Council on Alcohol Abuse and Alcoholism - September 2019

152nd Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism Presentation of the NIAAA Director's report, concept clearance, scientific presentation, ex officio updates and public commentsAir date: 9/12/2019 9:30:00 AM
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video

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Authors: Hughes TF, Liu A, Jacobsen E, Rosano C, Berman SB, Chang CH, Ganguli M Abstract INTRODUCTION: Although exercise is associated with a lower risk for mild cognitive impairment (MCI), it is unclear whether its protective effect depends on the presence or absence of vascular factors. METHODS: In an exploratory study of data from a population-based cohort, 1254 participants aged 65+ years were followed for 10 years for incident MCI. The main effect of baseline total minutes of exercise per week (0 vs. 1 to 149 vs. 150+), and its interaction with several vascular factors, on risk for incident MCI was examine...
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research
HOW TO sleep: Many Britons struggle to get a good night's rest and throwing alcohol in the mix equals a restless night and complete exhaustion the next day. How exactly does alcohol affect the body and one's sleep and is there any food which could help combat this?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
OBJECTIVES: To review the metrics and findings of studies evaluating effects of drug decriminalisation or legal regulation on drug availability, use or related health and social harms globally. DESIGN: Systematic review with narrative synthesis. DA...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
This study aimed to assess inpatient prevalence, characteristics, outcomes, and resource utilization of hospitalization for methanol intoxication in the United States. MATERIALS AND METHODS: A total of 603 hospitalized patients with a prima...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
The majority of vehicle accidents are attributable to driver error, such as substance use, distractions, fatigue, speeding, and driving experience. Many of these driver errors are also associated with delay discounting, where individuals that excessively d...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
The future of survey research in the alcohol field, as elsewhere, does look gloomy. Even if there is a need to better confront this reality, abandoning traditional survey methods does not guarantee better outcomes and is not an equally burning issue in all...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Notice NOT-AA-20-021 from the NIH Guide for Grants and Contracts
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Authors: Miyata T, Nagy LE Abstract Alcohol-associated liver disease (ALD), which ranges from mild disease to alcohol-associated hepatitis and cirrhosis, is the most prevalent type of chronic liver disease and a leading cause of morbidity and mortality worldwide. Accumulating evidence reveals that programmed cell death (PCD) plays a crucial role in progression of ALD involving crosstalk between hepatocytes and immune cells. Multiple pathways of PCD, including apoptosis, necroptosis, autophagy, pyroptosis and ferroptosis, are reported in ALD. Interestingly, PCD pathways are intimately linked and interdependent, maki...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
Authors: Kondo R, Iwakiri Y Abstract The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD. PMID: 32951411 [PubMed - as supplied by publisher]
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
Authors: Kim YS, Kim SG Abstract Alcoholic and non-alcoholic liver diseases begin from an imbalance in lipid metabolism in hepatocytes as the earliest response. Both liver diseases share common disease features and stages (i.e., steatosis, hepatitis, cirrhosis, and hepatocellular carcinoma). However, the two diseases have differential pathogenesis and clinical symptoms. Studies have elucidated the molecular basis underlying similarities and differences in the pathogenesis of the diseases; the factors contributing to the progression of liver diseases include depletion of sulfhydryl pools, enhanced levels of reactive...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
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