Value of VAV3 Methylation in Stool DNA Might Be Restricted to Non –Thiopurine-Treated Inflammatory Bowel Disease Patients

Fecal testing in general and fecal immunochemical testing for hemoglobin in particular have become important screening modalities for the prevention and early detection of sporadic colorectal cancer (CRC). Constant improvements in feces-based screening methodology now have resulted in satisfactory sensitivity and specificity, even in population-wide approaches.1 However, the use of fecal immunochemical testing is less suitable for specific patient populations at risk for CRC, especially in patients with inflammatory bowel disease (IBD), who often display colonic luminal bleeding resulting from ulceration.

Source: Clinical Gastroenterology and Hepatology - June 16, 2019 Category: Gastroenterology Authors: Suk Yee Lam, Jun Yu, Maikel. P. Peppelenbosch Tags: Letter to the Editor Source Type: research