Impaired sleep quality is associated with concurrent elevations in inflammatory markers: are post-menopausal women at greater risk?

ConclusionImpaired sleep quality is independently associated with greater inflammation in healthy adult men and women. Despite an overall less favorable metabolic and inflammatory profile in postmenopausal women, impaired sleep did not emerge as differentially related to inflammatory activity in this group.
Source: Biology of Sex Differences - Category: Biology Source Type: research

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ConclusionsA history of MST is common among older women veterans and associated with a range of medical and mental health diagnoses. These findings call attention to the need for additional research in this understudied population, and the importance of trauma-informed care approaches for women across the lifespan.
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
The perimenopause describes the phase of transition from regular menstruation to its cessation. It is characterized by physical and emotional changes and is determined by biological, psychological and socio-cultural aspects within the aging process [1,2]. During this transition, women often report psychological, somatic, vasomotor, and urogenital symptoms [3,4]. Up to 70% of all women experience symptoms such as hot flushes, night sweats or sleep disturbances [5]. Besides physical symptoms, the menopausal transition is a critical phase for psychological disorders such as depression and anxiety [6 –11].
Source: Maturitas - Category: Primary Care Authors: Source Type: research
Conclusions: We extend existing research by demonstrating that hormone therapy (HT) in subjective sleep cannot be fully explained by improvements in VMS bother or depressive symptoms. Research to examine the mechanism (s) underlying HT's effects on sleep would have public health significance for perimenopausal women and also advance our general understanding of the pathophysiology of impaired sleep.
Source: Menopause - Category: OBGYN Tags: Brief Report Source Type: research
Objective: The aim of this study was to explore the association of self-reported physical fitness (PF) and its components with cardiometabolic and mental health in perimenopausal women. Methods: These cross-sectional analyses included 191 participants (53 ± 4 y old) from the FLAMENCO project. Self-reported PF was assessed with the International Fitness Scale (IFIS). Body mass index (BMI), fat mass (FM), waist circumference (WC), systolic and diastolic blood pressure (DBP), high-density lipoprotein cholesterol (HDL-C), triglycerides, C-reactive protein (CRP), and glucose were measured. The Beck's Depression ...
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
By 2025, the number of postmenopausal women is expected to approach 1.1 billion worldwide [1]. A majority of women will develop symptoms during the menopausal transition, including but not limited to vasomotor symptoms (VMS), sleep disturbances, mood symptoms, and vaginal dryness [2]. It is important to understand the factors that may influence these symptoms given the rising number of symptomatic women, as well as the significant negative effect these symptoms may have on quality of life [3]. Relationship satisfaction is known to affect health outcomes positively, many times through dyadic coping strategies that may mitig...
Source: Maturitas - Category: Primary Care Authors: Source Type: research
CONCLUSIONS: Mindfulness meditation training can effectively alleviate the symptoms of anxiety and depression and improve the quality of sleep in perimenopausal women, and the frequency of the exercise is positively correlated with the improvements. Mindfulness meditation training can be an effective intervention for improving the mental health of perimenopausal women. PMID: 31511223 [PubMed - in process]
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research
Objective: To evaluate the effectiveness of cognitive behavioral therapy for menopausal symptoms (CBT-Meno) compared with a waitlist condition (no active intervention). A randomized controlled trial was conducted with 71 perimenopausal or postmenopausal women who were seeking treatment for menopausal symptoms. Methods: Blind assessments were conducted at baseline, 12 weeks postbaseline, and 3 months post-treatment. An intention-to-treat analysis was conducted. CBT-Meno sessions included psychoeducation, and cognitive and behavioral strategies for vasomotor and depressive symptoms, anxiety, sleep difficulties, and sexu...
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
AbstractThere are 3 common physiological estrogens, of which estradiol (E2) is seen to decline rapidly over the menopausal transition. This decline in E2 has been associated with a number of changes in the brain, including cognitive changes, effects on sleep, and effects on mood. These effects have been demonstrated in both rodent and non-human preclinical models. Furthermore, E2 interactions have been indicated in a number of neuropsychiatric disorders, including Alzheimer ’s disease, schizophrenia, and depression. In normal brain aging, there are a number of systems that undergo changes and a number of these show i...
Source: Neurotherapeutics - Category: Neurology Source Type: research
Resumo O objetivo deste artigo é identificar a prevalência de perda da qualidade do sono em mulheres climatéricas e os fatores associados. Estudo quantitativo, transversal e analítico, cujas variáveis foram investigadas por questionário estruturado/pré-testado e pelo Índice de Qualidade do Sono de Pittsburgh, em 819 mulhe res climatéricas assistidas pela Estratégia Saúde da Família. Regressão de Poisson simples foi utilizada para triagem das variáveis (p
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
Menopause is characterized by the onset of vasomotor symptoms (VMS) and genitourinary syndrome of menopause (GSM) and it often features changes in mood, sleep patterns, memory and body shape. The Study of Women ’s Health Across the Nation (SWAN) showed that in the premenopausal age group the prevalence of sleep disturbance ranges from 16% to 42%, in perimenopausal women from 39% to 47%, and in postmenopausal women from 35% to 60% (1). Sleep disorders among menopausal women have been linked to several fac tors: normal physiological changes associated with aging, menopause-related symptoms, stress, mood symptoms (depre...
Source: Maturitas - Category: Primary Care Authors: Source Type: research
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