Association between First Trimester Antidepressant Use and Risk of Spontaneous Abortion

ConclusionThe association between use of first trimester antidepressants, particularly SSRI use, and spontaneous abortion was significant only among women whose exposure status was assessed after loss. In this instance, reporting bias may create a spurious association. Future studies should take the timing of data collection relative to the timing of loss into consideration.This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Original Research Article Source Type: research

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AbstractThe time between arrest of pregnancy development and miscarriage represents a window in which the pregnancy is nonviable and not developing. In effect, the pregnancy loss has already occurred, and additional exposure cannot influence its outcome. However, epidemiologic studies of miscarriage traditionally use gestational age at miscarriage (GAM) to assign time in survival analyses, which overestimates duration of exposure and time at risk. In Right From the Start, a pregnancy cohort study (2000 –2012), we characterized the gap between estimated gestational age at arrest of development (GAAD) and miscarriage u...
Source: American Journal of Epidemiology - Category: Epidemiology Source Type: research
Conclusions: KCl injection under ultrasonographic guidance could be a safer and more effective treatment option than surgical treatment in hemodynamically stable patients with fetal cardiac activity in interstitial pregnancy. Expectant management could be an option for patients with no fetal cardiac activity. PMID: 31432733 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
ConclusionIn women with endometrial polyps the prevalence of CE is higher in those with infertility compared to women without infertility. Pregnancy outcome of infertile women with treated CE was similar to those with infertility and without CE.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: Available online 20 August 2019Source: Journal of Trace Elements in Medicine and BiologyAuthor(s): Margarita G. Skalnaya, Alexey A. Tinkov, Yulia N. Lobanova, Jung-Su Chang, Anatoly V. SkalnyAbstractBackgroundIron (Fe), copper (Cu), and manganese (Mn) play a significant role in female reproduction and fetal development. At the same time, high levels of metals may exert toxic effects. Correspondingly, both excess and deficiency of essential trace elements were shown to be associated with female infertility and adverse pregnancy outcome, although the existing data are rather contradictory. Therefore, the ob...
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
Emma Ginn, the director of Medical Justice, warns that women in immigration detention receive inadequate healthcareYou report how a pregnant rape survivor experiencing a miscarriage and barely able to stand was unlawfully held in immigration detention which amounted to inhuman and degrading treatment (Home Office pays £50,000 to trafficked woman detained during miscarriage, 20 August).This case show precisely why the Home Office must heed our advice and that of the medical profession, and actually ban the detention of pregnant women.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Immigration and asylum Women Pregnancy Health & wellbeing Home Office Politics Medical research Human rights Source Type: news
Publication date: Available online 19 August 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): Emma Sharkey, Siân GriffithsAbstractAnaesthesia, surgery and ionizing radiation may all prove harmful to an undetected pregnancy. Elective procedures should be deferred at least until the second trimester to reduce the risk of teratogenicity or spontaneous abortion. If surgery cannot be delayed, anaesthetic or surgical techniques can be modified, and the use of intraoperative ionizing radiation avoided where possible. Determination of pregnancy status is mandated by current national guidelines prior to any proc...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Abstract OBJECTIVES: The aim of this study was to evaluate the natural history and outcome of selective fetal growth restriction (sFGR) in monochorionic diamniotic (MCDA) twin pregnancies, according to the gestational age at onset and the various reported diagnostic criteria, and to quantify the risk of superimposed twin-to-twin transfusion syndrome (TTTS). METHODS: This is a cohort study of MCDA twin pregnancies that had their routine antenatal care from the first trimester at St George's Hospital, London. These pregnancies had ultrasound scans every 2 weeks at 16-24 weeks, and then every 2-3&t...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
MONDAY, Aug. 19, 2019 -- Alcohol consumption during pregnancy is associated with a dose-dependent increase in miscarriage risk, according to a review published in the August issue of Alcoholism: Clinical&Experimental Research. Alexandra C....
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
To assess whether the peri-conceptional or pregnancy exposure of human papillomavirus (HPV) vaccination would increase the risk of spontaneous abortion.
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
CONCLUSION: The results confirm the importance of studies involving Social Determinants of Health, since they interfere in the way women choose birth control methods and the risks that this choice may pose to their health. PMID: 31432964 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research
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