Effect of pre-operative oral carbohydrate loading on recovery after day-case cholecystectomy: A randomised controlled trial

CONCLUSION Compared with overnight fasting, pre-operative carbohydrate loading did not significantly enhance peri-operative well being or recovery in patients undergoing day-case cholecystectomy. TRIAL REGISTRATION Clinicaltrials.gov Identifier: NCT03757208.
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Fluids Source Type: research

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Contributors : Kristoffer G Rigbolt ; Helene ÆgidiusSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo improve the understanding of the complex biological processes underlying the development of non-alcoholic steatohepatitis (NASH), a multi-omics approach combining bulk RNA-sequencing based transcriptomics, quantitative proteomics and single-cell RNA-sequencing was used to characterize tissue biopsies from histologically validated diet-induced obese (DIO) NASH mice compared to chow-fed controls. Bulk RNA-sequencing and proteomics showed a clear distinction between phenotypes and...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
The objectives of this article are the following: 1) to examine fibromyalgia and somatic symptom disorder analogy. 2) to discuss stress-evoked neuropathic pain sexual dimorphism, and 3) to propose a neuropathic pathogenesis that may explain how stressed women could develop fibromyalgia. Recent research demonstrates a clear link between fibromyalgia and small fibre neuropathy. Dorsal root ganglia contain the small nerve fibre nuclei. In rodents, physical, chemical, or environmental stressors lead to dorsal root ganglia phenotypic changes and to hyperalgesia. This phenomenon is much more frequent in females. Prolactin, oestr...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: van Campen C(MC, Rowe PC, Verheugt FWA, Visser FC Abstract OBJECTIVES: Muscle pain and fibromyalgia (FM) are common among individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We recently demonstrated that during orthostatic stress testing, adults with ME/CFS reported increased pain. In the current study, we hypothesised that pain pressure thresholds (PPT) would decrease and temporal summation (windup) would increase after head-up tilt testing (HUT), and that the presence of co-morbid FM would be associated with greater change in both measures. METHODS: We studied adult ME/CFS p...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: Campana C, Corica G, Nista F, Cocchiara F, Graziani G, Khorrami K, Franco M, Boschetti M, Ferone D, Gatto F Abstract INTRODUCTION: Acromegaly is a disease characterized by elevated growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels. Surgery is the only curative treatment, while medical therapies are administered lifelong. To date, almost 30% of patients treated with the currently available medical therapies do not achieve biochemical control. AREAS COVERED: This review focuses on new drugs in development for acromegaly. In detail, we provide an overview of the new molecules designed to...
Source: Expert Opinion on Emerging Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Emerg Drugs Source Type: research
Authors: Beshel JA, Beshel FN, Nwangwa JN, Asuquo IO, Ejim CI, Owu DU Abstract BACKGROUND: Antioxidants are beneficial in myocardial infarction (MI). It is suggestive that Theobroma cacao (TC) with rich antioxidant properties can be of health benefit in myocardial injury. AIM: The study investigated the effect of Theobroma cacao on cardioprotection in isoproterenol-induced myocardial infarc-tion in rats. MATERIAL AND METHODS: Male Wistar rats divided into four groups of 6 rats were used for the study. Group 1, the control was administered 0.9% normal saline placebo via oral gavage. Group 2 was the MI induce...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - Category: Cardiology Tags: Cardiovasc Hematol Agents Med Chem Source Type: research
Publication date: 1 January 2021Source: Carbohydrate Polymers, Volume 251Author(s): Matteo Cibinel, Giorgia Pugliese, Davide Porrelli, Lucia Marsich, Vanni Lughi
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: 1 January 2021Source: Carbohydrate Polymers, Volume 251Author(s): Xin Wei, Guang-Lei Liu, Shu-Lei Jia, Zhe Chi, Zhong Hu, Zhen-Ming Chi
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: 1 January 2021Source: Carbohydrate Polymers, Volume 251Author(s): Fenghua Tao, Sijia Ma, Hai Tao, Lin Jin, Yue Luo, Jian Zheng, Wei Xiang, Hongbing Deng
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Contributors : Haowei Jiang ; Morgan Newman ; Stephen Pederson ; Michael LardelliSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioAlzheimer ’s disease is the most common form of age-related dementia. At least 15 mutations in the human gene PRESENILIN 2 (PSEN2) have been found to cause familial Alzheimer’s disease (fAD). Zebrafish possess an orthologous gene, psen2, and present opportunities for investigation of PRESENILIN function r elated to Alzheimer’s disease. The most prevalent and best characterized fAD mutation in PSEN2 is N141I. The equivalent codon in zebrafish...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Danio rerio Source Type: research
Discussion: The use of biologic agents did not increase in this interval, but it is higher than in an earlier assessment of the NAMCS. Nearly all systemic immunomodulators are prescribed by dermatologists. The ambulatory uptake of these agents did not alter the use of other treatment modalities within this timeframe. PMID: 32940551 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
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