Lessons from next generation influenza vaccines for inflammatory disease therapies.

Lessons from next generation influenza vaccines for inflammatory disease therapies. Int Immunopharmacol. 2019 Jul 04;74:105729 Authors: Zimmerman DH, Carambula RE, Ciemielewski J, Rosenthal KS Abstract Lessons can be learned for treating inflammatory diseases such as rheumatoid arthritis (RA) from next generation approaches for development of universal influenza vaccines. Immunomodulation of inflammatory diseases, rather than ablation of cytokine or cellular responses, can address the root cause of the disease and provide potential cure. Like influenza, there are different antigenic 'strains' and inflammatory T cell responses, Th1 or Th17, that drive each person's disease. As such, next generation vaccine-like antigen specific therapies for inflammatory diseases can be developed but will need to be customized to the patient depending upon the antigen and T cell response that is driving the disease. PMID: 31280056 [PubMed - as supplied by publisher]
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Tags: Int Immunopharmacol Source Type: research