Renal Artery Denervation in Resistant Hypertension: The Good, The Bad and the Future

Early studies of renal artery denervation (RAD) demonstrated efficacy in treating resistant hypertension patients with significant reduction in office blood pressure (BP). This resulted in a growing enthusiasm in the field and a rapid evolution of technology with expanding procedural indications. However, the first randomised sham-controlled trial, Symplicity HTN-3, failed to demonstrate a significant difference in BP reduction between the RAD and the sham control arm, which subsequently led to a major drawback in the clinical application of this procedure.

Source: Heart, Lung and Circulation - July 5, 2019 Category: Cardiology Authors: Sara I. Al Raisi, Jim Pouliopoulos, John Swinnenc, Aravinda Thiagalingam, Pramesh Kovoor Tags: Review Source Type: research