Genomic imprinting and its effects on postnatal growth and adult metabolism.

Genomic imprinting and its effects on postnatal growth and adult metabolism. Cell Mol Life Sci. 2019 Jul 03;: Authors: Millership SJ, Van de Pette M, Withers DJ Abstract Imprinted genes display parent-of-origin-specific expression with this epigenetic system of regulation found exclusively in therian mammals. Historically, defined imprinted gene functions were almost solely focused on pregnancy and the influence on the growth parameters of the developing embryo and placenta. More recently, a number of postnatal functions have been identified which converge on resource allocation, both for animals in the nest and in adults. While many of the prenatal functions of imprinted genes that have so far been described adhere to the "parental conflict" hypothesis, no clear picture has yet emerged on the functional role of imprints on postnatal metabolism. As these roles are uncovered, interest in the potential for these genes to influence postnatal metabolism and associated adult-onset disease outcomes when dysregulated has gathered pace. Here, we review the published data on imprinted genes and their influence on postnatal metabolism, starting in the nest, and then progressing through to adulthood. When observing the functional effects of these genes on adult metabolism, we must always be careful to acknowledge the influence both of direct expression in the relevant metabolic tissue, but also indirect metabolic programming effects caused by their modula...
Source: Cellular and Molecular Life Sciences : CMLS - Category: Cytology Authors: Tags: Cell Mol Life Sci Source Type: research

Related Links:

Source: BMJ Comments - Category: General Medicine Source Type: forums
Javaid Perwaiz, an obstetrician and gynecologist, was arrested and charged with health care fraud. In one instance, he was accused of tying one patient ’s fallopian tubes without her knowledge, according to court documents.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Hysterectomies Malpractice Pregnancy and Childbirth Virginia Javaid Perwaiz Frauds and Swindling Source Type: news
Study points out dangers, provides tips on monitoring health of mother and baby.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
The the link between a pregnant woman's smoking and her baby's risks for sudden infant death syndrome. An Arizona University study in rats suggests how nicotine may alter their breathing.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
[Nation] The national commitments resulting from the 1994 International Conference on Population and Development have delivered real gains in health, gender equity, and reproductive rights.
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
Publication date: Available online 10 November 2019Source: Preventive Veterinary MedicineAuthor(s): Eliana Lima, Fiona Lovatt, Martin Green, Janet Roden, Peers Davies, Jasmeet KalerAbstractIn light of current concerns about the sustainability of red meat production in a world with increasing global demand for food from animal origin there is a need for a better understanding of factors that influence the growth rate and feed conversion efficiency of animals on commercial farms. The primary objective of this observational study was to use longitudinal data to quantify the simultaneous effects of multiple ewe and lamb factor...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
According to a study presented at the Society for Endocrinology annual conference in Brighton, liver disease during pregnancy may alter gut bacteria composition and increase risk of childhood obesity.Scienmag
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
The feeling of abandonment can span through all types of relationships and in this episode, we focus on friendships. Have you ever had a close friend abandon you or have you ever exited a friendship without notice? The emotions and actions surrounding the abandonment of friends can be complex and hurtful, but they are very real and can hurt deeply.  In this episode, Jackie recounts friendships that were very important to her and how she’s handling the loss of them. (Transcript Available Below) SUBSCRIBE &REVIEW About The Not Crazy Podcast Hosts Gabe Howard is an award-winning writer and speaker who live...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Communication Family Friends General Grief and Loss Not Crazy Podcast Relationships Source Type: blogs
OBJECTIVE: To examine the association between various types of domestic violence (DV) during pregnancy (emotional violence, physical violence, and sexual violence) and pre-term or low birthweight delivery in women living in Ho Chi Minh city, Vietnam. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
-- Pets may feel like part of the family. But when you're pregnant, you need to be careful and care for your pets in a way that is safe, says the March of Dimes. For pregnant women who own pets, the March of Dimes suggests: Do not let your pet...
Source: - Daily MedNews - Category: General Medicine Source Type: news
More News: Cytology | Genetics | Pregnancy