Antiarrhythmic efficacy of CPUY102122, a multiple ion channel blocker, on rabbits with ischemia/reperfusion injury.

CONCLUSIONS: These results indicated that CY22 has both antiarrhythmic and cardiovascular protective effects partly by blocking IKr, the production of antioxidants and protection of Cx43.
PMID: 25443730 [PubMed - in process]

Source: Pharmacological Reports - December 1, 2014 Category: Drugs & Pharmacology Authors: Wang M, Shan J, Yang Q, Ma X, Jin S, Guo X, You Q, Tang Y Tags: Pharmacol Rep Source Type: research