Biodistribution and radiation dosimetry of the novel hypoxia PET probe [ 18 F]DiFA and comparison with [ 18 F]FMISO

Conclusion[18F]DiFA is well tolerated, and its radiation dose is comparable to those of other hypoxia tracers. [18F]DiFA is very rapidly cleared via the urinary system. [18F]DiFA PET generated comparable images to [18F]FMISO PET in hypoxia imaging with shorter waiting time, demonstrating the promising potential of [18F]DiFA PET for hypoxia imaging and for a multicenter trial.

http://link.springer.com/10.1186/s13550-019-0525-6

Source: EJNMMI Research - July 4, 2019 Category: Radiology Source Type: research