Schisandrin B inhibits TGF- β1-induced epithelial-mesenchymal transition in human A549 cells through epigenetic silencing of ZEB1.

Conclusions: Our data suggest that Sch B can prevent TGF-β1-stimulated EMT in A549 cells through epigenetic silencing of ZEB1, which may be clinically related to the efficient treatment of EMT-associated fibrotic diseases. PMID: 31268360 [PubMed - as supplied by publisher]
Source: Experimental Lung Research - Category: Respiratory Medicine Tags: Exp Lung Res Source Type: research