Epithelioid sarcoma involving sciatic nerve with lung metastasis and local recurrence: A case report

We report a rare case of epithelioid sarcoma involved the sciatic nerve which presented with chronic sciatic pain and treated with radically wide resection, but lung metastasis and local recurrence have occurred shortly after surgical resection and resulting in the patient's death in six months after initial presentation.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research

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The objective of this study was to evaluate the potential analgesic action of 8% capsaicin cream for topical use in patients with myofascial pain syndrome. METHODS: Initially, cream formulations of PLA (Placebo) and CPS (Capsaicin 8%) were developed and approved according to the current requirements of the health authority agency. The 40 participating patients were randomly assigned to the PLA and CPS groups in a double-blind fashion. Before the creams were topically administered, according to the allocation group, the local anesthetic was used for a period of 50minutes directly in the area of interest. The cream was a...
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Publication date: Available online 14 September 2019Source: Reumatología Clínica (English Edition)Author(s): Manuel Jiménez Ortiz, Alfonso Espinosa Ruiz, Cristóbal Martínez Delgado, Pablo Barrena Sánchez, José A. Salido ValleAbstractBackgroundThe association of depression and chronic pain in knee osteoarthritis is a complex and difficult phenomenon to understand. In fact, establishing the order of appearance of these entities might result in an arduous task.ObjectiveIn addition to analysing the relationship between preoperative anxiety and depression according to the results...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
Publication date: Available online 14 September 2019Source: Heart &LungAuthor(s): Zenghui Zhang, Jun GuoAbstractBackgroundLeft ventricular aneurysm (LVA) is a severe complication of ST-elevation myocardial infarction (STEMI) and is associated with poor prognosis due to high mortality. However, predictors of LVA formation in early period are inadequately defined.ObjectivesThe purpose of this study is to determine potential predictors of LVA formation in early period (
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
ConclusionsEndovascular coil fiducial placement for lung SBRT is associated with high procedural success rates and lower rates of clinically relevant complications than transthoracic marker placement.
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
Conclusions: Women with deep invasive endometriosis who underwent IVF do not seem to be exposed to a substantially increased risk of recurrence/disease progression. Larger evidence from independent groups is however required for a definitive conclusion. PMID: 31517304 [PubMed]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Eur J Obstet Gynecol Reprod Biol X Source Type: research
Conclusions: A wide variety of analgesia protocols are used. The three most frequently used are i.v. administered opioids, i.m. administered opioids, and non-sedative oral analgesics. The variety of analgesia protocols is not desirable in the context of good clinical practice, and considering the risks of combining opioids and benzodiazepines. Monitoring of vital functions was only performed after administration of i.v. medication. A comparison of the pain scores could be a first step in finding the optimal method of analgesia, thereby forming the basis of guidelines for analgesia during oocyte retrieval. PMID: 31517299 [PubMed]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Eur J Obstet Gynecol Reprod Biol X Source Type: research
In conclusion, miR-101 had neuropathic pain-attenuating activity through targeting mTOR.
Source: Neuroscience Research - Category: Neuroscience Source Type: research
This week, I sat, enthralled in a darkened movie theater watching a story unfold. Before the first scene, the line, “Based on an actual lie,” ran across the screen. The film is called The Farewell and is the story of the lung cancer diagnosis of the filmmaker’s grandmother. Lulu Wang is the director for whom art imitates life. Her alter ego is Billi, played by the actress and rapper Akwafina. Billi adores her Nai Nai (Chinese for grandmother), who assisted in raising her when her parents immigrated to the U.S. when she was a child. She discovers that her grandmother was diagnosed with end stage lung cance...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Grief and Loss Health-related Bereavement grieving Source Type: blogs
As a GP, I know opioids have their place. But we shouldn ’t be complacent about a US-style crisis happening in BritainGrowing concern about the prescription of drugs that cause dependence has been backed up by a recent report from Public Health England (PHE). The agencydiscovered that in 2017-18, 13% of adults in England received at least one prescription for opioids such as morphine or oxycodone (although this represented a slight downturn in prescribing after a long upward trend). Other drug classes were implicated too, with 25% of adults prescribed one or more of the following drugs: benzodiazepines (such as Valiu...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Opioids GPs NHS Doctors Health Society Drugs policy Politics Science UK news Source Type: news
Authors: Segarra AB, Prieto I, Martinez-Canamero M, Ruiz-Sanz JI, Ruiz-Larrea MB, De Gasparo M, Banegas I, Zorad S, Ramirez-Sanchez M Abstract OBJECTIVE: Enkephalins are neuropeptides involved in functions such as pain modulation and/ or cognitive processes. It has been reported that dietary fat modifies enkephalins in the brain. Since enkephalins are hydrolyzed by enkephalinases, the study of the influence of dietary fats, differing in their degree of saturation, on brain fatty acids content and enkephalinase activity is important to understand its regulatory role on neuropeptides under different type of diets. ...
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research
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