ICD-9 tobacco use codes are effective identifiers of smoking status.
ICD-9 tobacco use codes are effective identifiers of smoking status. J Am Med Inform Assoc. 2013 Feb 9; Authors: Wiley LK, Shah A, Xu H, Bush WS Abstract OBJECTIVE: To evaluate the validity of, characterize the usage of, and propose potential research applications for International Classification of Diseases, Ninth Revision (ICD-9) tobacco codes in clinical populations. MATERIALS AND METHODS: Using data on cancer cases and cancer-free controls from Vanderbilt's biorepository, BioVU, we evaluated the utility of ICD-9 tobacco use codes to identify ever-smokers in general and high smoking prevalence (lung cancer) clinic populations. We assessed potential biases in documentation, and performed temporal analysis relating transitions between smoking codes to smoking cessation attempts. We also examined the suitability of these codes for use in genetic association analyses. RESULTS: ICD-9 tobacco use codes can identify smokers in a general clinic population (specificity of 1, sensitivity of 0.32), and there is little evidence of documentation bias. Frequency of code transitions between 'current' and 'former' tobacco use was significantly correlated with initial success at smoking cessation (p
Conclusions: Adrenal SBRT for oligometastatic disease is a feasible, noninvasive option with excellent LC and minimal toxicity. Lesions in close proximity to radiosensitive organs may benefit from dynamic patient positioning and selective simultaneous-integrated boost techniques to allow for dose escalation, while also limiting toxicity risks.
Conclusions: This review of outcomes of RT for ICM in LC demonstrates a higher rate of RN than previously reported in the literature in those having had a surgical resection plus stereotactic radiosurgery. Our observation of RN as late as 5 years post-RT for ICM necessitates clinician awareness.
Publication date: Available online 24 January 2020Source: The Annals of Thoracic SurgeryAuthor(s): Omar Toubat, Scott M. Atay, Anthony W. Kim, Li Ding, Albert J. Farias, Peggy J. Ebner, P. Michael McFadden, Elizabeth A. DavidAbstractBackgroundSocioeconomic status (SES) disparities in the surgical management of patients with non-small cell lung cancer (NSCLC) are well-described. Disparities in the receipt of adjuvant chemotherapy are poorly understood. We assessed the influence of SES on adjuvant chemotherapy following resection in patients with pN1 NSCLC.MethodsThe National Cancer Database was queried for cN0/N1 NSCLC pati...
We present a case where nocardial abscesses of lung and brain were initially suspected as lung cancer with brain metastases. The patient was treated with a combination of surgical resection and antimicrobial therapy with good outcome. PMID: 31969769 [PubMed - in process]
An immune system that's not functioning normally may lead to lung cancer in patients who don't smoke, a new study suggests.
What is a coronavirus? Coronaviruses are a group of viruses that cause diseases in mammals, including humans, and birds. Why are they called coronaviruses? The name derives from the fact that the viral capsule has a “halo” or “crown” surrounding it. What do coronaviruses do? In humans, the virus infects the airways giving rise to flu-like symptoms, a runny nose, cough, sore throat and fever, these are usually mild, but in rare cases can be lethal. Is there a vaccine against coronaviruses? No. Are there any drugs to block or treat infection? No. When were coronaviruses first discovered? In the 1960s ...
We present a unique and successful case of a young patient with primary refractory ALK-positive LBCL who received salvage chemotherapy plus brigatinib followed by allogeneic stem cell transplantation.
FRIDAY, Jan. 24, 2020 -- An immune system that's not functioning normally may lead to lung cancer in patients who don't smoke, a new study suggests. " A strong immune system helps to keep inflammation under control and chronic inflammation is known...
In conclusion, NR2F2-AS1 downregulation decreased proliferation and increased apoptosis of NPC cells via upregulation of PTEN. PMID: 31966043 [PubMed]