Activation of the Peroxisome Proliferator –Activated Receptor γ Coactivator 1β/NFATc1 Pathway in Circulating Osteoclast Precursors Associated With Bone Destruction in Rheumatoid Arthritis

ConclusionActivation of the PGC ‐1β/NFATc1 pathway in circulating osteoclast precursors was associated with bone destruction in RA. This may represent a new treatment target.

Source: Arthritis and Rheumatology - July 2, 2019 Category: Rheumatology Authors: Jian ‐Da Ma, Jun Jing, Jun‐Wei Wang, Ying‐Qian Mo, Qian‐Hua Li, Jian‐Zi Lin, Le‐Feng Chen, Lan Shao, Pierre Miossec, Lie Dai Tags: Original Article Source Type: research