Bidirectional Association between First-Episode Panic Disorder and Major Depressive Disorder in a Nationwide General Population Survey in Korea.

CONCLUSION: The results revealed a bidirectional relationship between MDD and PD. Each disease represents a risk of a subsequent occurrence of the other, which lasts for a considerable duration. PMID: 31269543 [PubMed - in process]
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research

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Molecular Psychiatry, Published online: 11 November 2019; doi:10.1038/s41380-019-0590-2Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression
Source: Molecular Psychiatry - Category: Psychiatry Authors: Source Type: research
This study aimed to evaluate the bioequivalence between two formulations of clonazepam tablets in order to meet regulatory requirements for marketing in Colombia and others countries in Latin America. An open-label, randomized, single-dose, two-period, two-sequence, two-treatment crossover study was conducted in 36 healthy subjects of both genders. Subjects received a single dose of clonazepam 2 mg test tablet (Sanofi-Aventis de Colombia S.A.) and reference product (Rivotril®, Produtos Roche Químicos e Farmacêuticos S.A.) under fasting conditions according to a randomly assigned order with a 21-day ...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
Authors: Michalis G, Bellos S, Politis S, Magklara K, Petrikis P, Skapinakis P Abstract Background: The aim of the current study was to examine the prevalence and associations of hazardous alcohol use with sociodemographic variables and its comorbidity with depression and other common mental disorders in a sample of Greek adolescents between 16 and 18 year old. Methods: We recruited 2431 adolescents attending 25 senior high schools in Greece. We assessed depressive and anxiety disorders using the computerized version of a fully-structured psychiatric interview (the revised Clinical Interview Schedule / C...
Source: Depression Research and Treatment - Category: Psychiatry Tags: Depress Res Treat Source Type: research
  That’s precisely what the American Academy of Pediatrics (AAP) is recommending: more weight loss surgery for overweight kids. This sort of perverted advice reflects the deep and widespread failure of the healthcare system to address nutrition and health, resorting instead to an awful surgical “solution” that, contrary to the AAP’s declaration that it is a proven safe option, is filled with complications, nutritional deficiencies, dysbiotic alterations in bowel flora, hormonal disruptions, and—not all that rarely—death. (Granted that it was over 10 years ago, but the first patient ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open bariatric surgery gastric bypass lap bad Weight Loss wheat belly Source Type: blogs
Abstract Intolerance of uncertainty is a dispositional trait associated with a range of psychological disorders, but the influence of methodological factors on theses associations remains unknown. The first aim of this meta-analysis was to quantify the strengths of the association between IU and symptoms of generalised anxiety disorder, social anxiety disorder, panic disorder, agoraphobia, obsessive compulsive disorder, depression, and eating disorders. The second aim was to assess the influence of methodological factors on these relationships, including clinical (vs. non-clinical) status, age group, sex, IU measu...
Source: Clinical Psychology Review - Category: Psychiatry & Psychology Authors: Tags: Clin Psychol Rev Source Type: research
DiscussionThe results will supplement those of the cluster-randomized Collabri trials and provide pivotal information about the effects of collaborative care in Denmark.Trial registrationClinicalTrials.gov,NCT03113175 andNCT03113201. Registered on 13 April 2017.
Source: Trials - Category: Research Source Type: clinical trials
Conclusion: Major limitations of the reviewed studies were short trial duration, small sample sizes, and the lack of control groups. Defining the potential role of DUL in the treatment of psychiatric disorders other than major depressive disorder and generalized anxiety disorder needs further randomized, placebo-controlled studies.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
“If the only thing people learned was not to be afraid of their experience, that alone would change the world.” – Sidney Banks I spent most of my life scared of my feelings. Having feelings and expressing them made me mentally ill—or so I was led to believe by a large number of mental health professionals. When I felt sad, they labeled me as depressed. When I showed any signs of anxiety, they gave me another list of mental health disorders I needed medication for. And if I was angry? Oh well, that was the absolute worst. That clearly proved how insane and utterly out of control I was! I didn’...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic Personal Publishers Tiny Buddha Emotional Expression Emotions expressing feelings Source Type: blogs
Prescription of antidepressants is common among older adults, not just in the treatment of depression but also anxiety, panic disorder, neuropathic pain and urinary incontinence.1 Based on a Eurobarometer survey carried out in 27 European countries, 9.5% of adults aged 55 and over reported antidepressant use in the past year2 while Mars et al3 showed that antidepressant prescribing in the UK increased between 1995 and 2011, particularly in adults aged 46 and over. In older adults, antidepressant use has been associated with an increased likelihood of adverse outcomes such as cardiovascular events, hyponatremia, falls and f...
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Regular Research Article Source Type: research
Are you always in control and always perfectly put together? Are you professionally successful, a great friend, and always showing a happy face to the world?  But what about on the inside? Is there something in the background or in the past that you don’t talk about?  Do you feel disconnected, like no one knows the “real” you? Deep down do you just know something is wrong? Well, you might have “perfectly hidden depression.” Today Gabe speaks with Dr. Margaret Rutherford who has done extensive work on the relationship between perfectionism and depression.  Dr. Rutherford tells u...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Depression General Happiness Interview LifeHelper Mental Health and Wellness Perfectionism Personality Podcast Psychiatry Psychology Research Self-Esteem Self-Help The Psych Central Show Trauma Source Type: blogs
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