miR-15a: A Potential Diagnostic Biomarker and a Candidate for Non-operative Therapeutic Modality for Age-related Cataract.

CONCLUSIONS: The increased expression of hsa-miR-15a in lens epithelial cells of cataract patients may repress the expression of BCL-2 and MCL-1. The expression of hsa-miR-15a and the subsequent apoptosis of lens epithelial cells is part of the pathogenesis of age-related cataracts. PMID: 31264507 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31264507?dopt=Abstract

Source: British Journal of Biomedical Science - July 4, 2019 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research