Polyvascular subclinical atherosclerosis in familial hypercholesterolemia: the role of cholesterol burden and gender
Heterozygous familial hypercholesterolemia (HeFH) is a genetic disease characterized by a heterogeneous phenotype. The assessment of cardiovascular (CV) risk is challenging for HeFH. Cholesterol burden (CB) allows to estimate the lifelong exposure to high levels of cholesterol. The aim of this study was to analyze the distribution of subclinical atherosclerosis and the relationship between atherosclerosis and the CB in a sample of HeFH patients, focusing on sex-related differences.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Alessandro Mattina, Antonina Giammanco, Philippe Giral, David Rosenbaum, Alain Carri é, Philippe Cluzel, Alban Redheuil, Randa Bittar, Sophie Béliard, Davide Noto, Angelo Quartarone, Maurizio Averna, Éric Bruckert, Antonio Gallo Source Type: research