Performance of plasma measurement of neutrophil gelatinase-associated lipocalin as a biomarker of bacterial infections in the intensive care unit

ConclusionsIn our cohort of ICU patients, plasma dNGAL was associated with presence of bacterial infections independent of AKI but it performed poor as a predictor of infections. Following antibiotic therapy, dNGAL markedly decreased–supporting further exploration of dNGAL-guided antibiotic de-escalation.
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research