9. Next generation sequencing for myeloid neoplasms: a diagnostic management team approach

The hematopathology Diagnostic Management Team (DMT) utilizes decision-support algorithms to guide test ordering for bone marrow biopsies. Although next-generation sequencing (NGS) testing is commonly available for myeloid malignancies, there is little guidance on optimal utilization in the diagnosis and management of these diseases. We have incorporated marrow morphology into DMT algorithms for NGS testing, recommending testing only if there is morphologic evidence of disease at diagnosis or first presentation, transformation, or relapse.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Source Type: research