Pim ‐1 As a Therapeutic Target in Lupus Nephritis

ConclusionThese data identify Pim ‐1 as a critical regulator of LN pathogenesis in patients with SLE. Targeting of the Pim‐1/NFATc1/NLRP3 pathway might therefore have therapeutic potential in human LN.

Source: Arthritis and Rheumatology - July 1, 2019 Category: Rheumatology Authors: Rong Fu, Yong Xia, Meirong Li, Renxiang Mao, Chaohuan Guo, Mianjing Zhou, Hechang Tan, Meiling Liu, Shuang Wang, Niansheng Yang, Jijun Zhao Tags: Original Article Source Type: research