The neuropathology of liver, heart, and heart-lung transplantation

Martinez AJ, Puglia J
Source: The Aspergillus Website - articles - Category: Respiratory Medicine Source Type: news

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This study reported the inducing effect of Aspergillus flavus fungal elicitor on biosynthesis of terpenoid indole alkaloids (TIAs) in Catharanthus roseus cambial meristematic cells (CMCs) and its inducing mechanism. According to the results determined by HPLC and HPLC-MS/MS, the optimal condition of the A. flavus elicitor was as follows: after suspension culture of C. roseus CMCs for 6 day, 25 mg/L A. flavus mycelium elicitor were added, and the CMC suspensions were further cultured for another 48 h. In this condition, the contents of vindoline, catharanthine, and ajmaline were 1.45-, 3.29-, and 2.14-times as high as those...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
AbstractIn this work, a modified biomass material was successfully prepared by immobilization and inactivation method based onAspergillus niger, and the obtained environmentally friendly Alginate-immobilizedAspergillus niger microsphere (AAM) exhibited a superior Th(IV) biosorption performance. The sorption kinetics and thermodynamic analysis were studied and showed that the sorption process is spontaneous and endothermic under the experimental conditions. Additionally, the maximum biosorption capacity  of AAMs for Th(IV) can be of 303.95 mg g−1 at 313.15  K, which exhibited a superior biosorption...
Source: Journal of Radioanalytical and Nuclear Chemistry - Category: Nuclear Medicine Source Type: research
Aspergillus flavus, the primary causal agent for aflatoxin contamination on crops, consists of isolates with two distinct morphologies: isolates of the S morphotype produce numerous small sclerotia and lower numbers of conidia while isolates of the L morphotype produce fewer large sclerotia and abundant conidia. The morphotypes also differ in aflatoxin production with S isolates consistently producing high concentrations of aflatoxin, whereas L isolates range from atoxigenic to highly toxigenic. The production of abundant sclerotia by the S morphotype suggests adaptation for long-term survival in the soil, whereas the prod...
Source: G3: Genes Genomes Genetics - Category: Genetics & Stem Cells Authors: Tags: Investigations Source Type: research
Publication date: 25 April 2019Source: Food Chemistry, Volume 278Author(s): Mirella Rossitto Zanutto-Elgui, José Cavalcante Souza Vieira, Débora Zanoni do Prado, Marília Afonso Rabelo Buzalaf, Pedro de Magalhães Padilha, Deilson Elgui de Oliveira, Luciana Francisco FleuriAbstractBioactive peptides can provide health benefits due to different mechanisms. The aims of the present study are to produce bioactive peptides from bovine and goat milk subjected to the proteolytic activity of Aspergillus oryzae and Aspergillus flavipes enzymes, as well as to assess their putative antimicrobial and antioxid...
Source: Food Chemistry - Category: Food Science Source Type: research
We report a study conducted to investigate the variation on gene expression of the pathogenic fungus Aspergillus fumigatus upon co-cultivation with the pathogenic bacterium Pseudomonas aeruginosa. The study was conducted by investigating the gene expression variation at different time points (45, 90 and 180 minutes after co-incubation). As control, we used data obtained by cultivating the fungus either without bacteria, or with heat-inactivated Pseudomonas.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Aspergillus fumigatus A1163 Pseudomonas aeruginosa PAO1 Source Type: research
Authors: Hagiwara D Abstract Aspergillus fumigatus is a saprophytic fungus that is a major causative pathogen for aspergillosis. Only a few classes of antifungals are used for treating this life-threatening fungal infection. Azoles are the first-line drugs and are widely used for the management and prophylaxis of aspergillosis. An emerging issue is the increasing incidence of resistant isolates worldwide. In particular, environmentally derived tandem-repeat-type azole-resistant mutations, such as Cyp51A TR34/L98H, and Cyp51A TR46/Y121F/T289A, have emerged over the last decade. In particular, azole-resistant isolate...
Source: Medical Mycology Journal - Category: Biology Tags: Med Mycol J Source Type: research
Authors: Hagiwara D, Takahashi H, Takagi H, Watanabe A, Kamei K Abstract Stress responses and pathogenicity have been extensively studied in Aspergillus fumigatus, the main causative pathogen of life-threatening aspergillosis. The heterogeneity in this pathogen's biology has recently attracted increasing attention. In the present work, we used 16 clinically isolated strains to investigate several properties relevant to the pathogenicity of A. fumigatus, namely, gliotoxin production, elastase activity, hypoxia growth, adaptation to iron-limiting conditions, and growth upon nitrosative, oxidative, and high osmotic st...
Source: Medical Mycology Journal - Category: Biology Tags: Med Mycol J Source Type: research
Authors: Suzuki Y, Togano T, Ohto H, Kume H Abstract BACKGROUND AND METHODS: Our group has continuously studied the epidemiology of visceral mycoses (VM) among autopsy cases in Japan from 1989 to 2013. RESULTS: First, from a total of 11,149 autopsied cases, 571 (5.1%) cases of VM were observed in 2013. It was significantly higher than those of 2005 (p
Source: Medical Mycology Journal - Category: Biology Tags: Med Mycol J Source Type: research
In this study, we separated bacillomycin D-C14, D-C15, D-C16 monomers from the Bacillus subtilis strain fmbJ. The bacillomycin D monomers containing longer fatty acid chains better induced apoptosis in Bgc-823, Sgc-7901, and Hgc-27 gastric cancer cells. The Bgc-823 cell line was the most sensitive. Acridine orange-ethidium bromide staining indicated that bacillomycin D-C16-induced Bgc-823 cell death by triggering apoptosis, characterized by membrane blebbing, cellular shrinkage, and DNA fragmentation. Flow cytometric analysis showed a bacillomycin D-C16 dose-dependent trigger of Bgc-823 apoptosis. Bacillomycin D-C16-induce...
Source: Anti-Cancer Drugs - Category: Cancer & Oncology Tags: PRECLINICAL REPORTS Source Type: research
Publication date: Available online 5 December 2018Source: Microbial PathogenesisAuthor(s): Maneesha Palipane, John D. Snyder, Kim S. LeMessurier, Anna K. Schofield, Stacie N. Woolard, Amali E. SamarasingheAbstractAsthma and influenza are leading causes of worldwide morbidity and mortality. Although these two conditions can co-exist in the same patient, the immune parameters that impact disease outcomes are not fully elucidated. The importance of macrophages to both conditions suggested a role for CD14, a co-receptor for endotoxin, as a regulatory mechanism for innate immune responses during asthma and influenza co-morbidit...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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