Limited-Stage Small Cell Lung Cancer: Is Prophylactic Cranial Irradiation Necessary?

ConclusionOverall, PCI was associated with improved PFS and reduced early incidence of brain metastases. Patients achieving a CR to initial therapy did not experience a PFS benefit with PCI. This may indicate that subsets of LS-SCLC patients can potentially be spared from PCI in the era of modern imaging.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research