Predicting Risk for Dementia: Is It Ready for the Clinic?

Predicting Risk for Dementia: Is It Ready for the Clinic? Am J Psychiatry. 2019 Jul 01;176(7):501-502 Authors: Johnson SC, Asthana S PMID: 31256623 [PubMed - in process]
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research

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Cognitive testing at the age of 3 can predict how healthy a person ’s brain will be in their mid 40s, and may indicate whether they are likely to develop dementia
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Authors: Frausing KP, Stamp AS Abstract As the number of elderly citizens in general and the number of persons with dementia in particular rises, the importance of educating geriatric health care professionals increases. Recruitment is, however, impaired by negative stereotypes and insecurity. Previous research has shown that contact with the field of dementia care is important for students' motivation for choosing this career path. This paper presents an extracurricular psychomotor intervention program in which students through eight visits to elderly persons with dementia carry out an intervention involving direc...
Source: Gerontology and Geriatrics Education - Category: Geriatrics Tags: Gerontol Geriatr Educ Source Type: research
In this study, we examined the effect of PEG-AM on four-vessel occlusion model rats, which exhibit vascular dementia. From day 10 to day 14 after surgery, the learning and memory abilities of the rats were examined using a Morris water maze. The rats were treated with a single subcutaneous injection of 1.0 or 10.0 nmol/kg of PEG-AM. PEG-AM treatment reduced the escape latency in the hidden platform test. Furthermore, the treatment increased the time spent in the platform quadrant in the probe test. The data showed that PEG-AM injection prevented memory loss and learning disorders in dose-dependent manner. On day 14,...
Source: Peptides - Category: Biochemistry Source Type: research
Normal pressure hydrocephalus, which causes mobility and memory issues, can be mistaken for dementia.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
A little similar to thread below but would like you opinions! Learning a lot from these boards even after residency! Alone at night, patient brought in from nursing home,, 75 yo M 70kg ESRD, HTN, A fib on eliquis, DM, CAD LAD stent 10 yrs ago, CHF EF 10% on coreg, mod MR, mod TR , dementia, severe pHTN, reduced RV function w severely elevated CVP, fell, now w slowly expanding thigh hematoma needs to be drained. No detailed info/cath regarding CAD. Vitals normal/stable after 2 unit... How would you approach this case?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums
Publication date: Available online 23 August 2019Source: SeizureAuthor(s): Alessandro Orsini, Angelo Valetto, Veronica Bertini, Mariagrazia Esposito, Niccolò Carli, Berge A. Minassian, Alice Bonuccelli, Diego Peroni, Roberto Michelucci, Pasquale StrianoAbstractProgressive Myoclonus Epilepsies (PMEs) are a group of uncommon clinically and genetically heterogeneous disorders characterised by myoclonus, generalized epilepsy, and neurological deterioration, including dementia and ataxia. PMEs may have infancy, childhood, juvenile or adult onset, but usually present in late childhood or adolescence, at variance from epil...
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 23 August 2019Source: Alzheimer's &DementiaAuthor(s): Carla M. Startin, Sarah Hamburg, Rosalyn Hithersay, Tamara Al-Janabi, Kin Y. Mok, John Hardy, Andre Strydom
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Authors: Ma F, Lv X, Du Y, Chen H, Liu S, Zhao J, Gao Y, An P, Zhou X, Song A, Sun C, Wang G, Ji Y, Wang X, Xu W, Huang G Abstract BACKGROUND: Leukocyte telomere length (LTL) is associated with the aging process and age-related degenerative diseases. The relation of peripheral blood LTL to mild cognitive impairment (MCI) and Alzheimer's disease (AD) and the role of folate and homocysteine (Hcy) in this relation remain unclear. OBJECTIVES: We aimed to investigate the association between LTL and the risks of MCI/AD, and to explore whether folate and Hcy may play a role in this association. METHODS: This case-...
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Authors: Li B, He Y, Ma J, Huang P, Du J, Cao L, Wang Y, Xiao Q, Tang H, Chen S Abstract OBJECTIVE: Gut microbiota changes before the onset of Alzheimer's disease (AD) and the alterations could be detected in the stage of mild cognitive impairment (MCI). The findings might offer diagnostic biomarkers before the onset of dementia. BACKGROUND: AD is the most common cause of dementia, and MCI is the predementia state. Recent studies suggest the alterations in the gut microbial communities associated with AD, whereas the microbiota in MCI before the onset of dementia has not been discovered and characterized in hum...
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
ConclusionsThis population-based retrospective cohort study provides evidence that patients newly-diagnosed with dementia who showed higher initial drug compliance or maintained antidementia drugs (Cholinesterase inhibitors and memantine) would benefit in total health-care costs.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
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