Improvement in Gastrointestinal Symptoms From Light Chain Amyloidosis After Adalimumab Therapy

A 63-year-old man presented with a history of abdominal pain, diarrhea, and weight loss. He had an abdominal computed tomography scan, which revealed duodenal, jejunal, and colonic thickening. This was followed by colonoscopy with biopsies, and the patient was diagnosed with inflammatory bowel disease, likely Crohn disease. However, upper endoscopy was performed, which revealed duodenal thickening, and biopsy revealed amyloid deposits by Congo red staining. Stool cultures were negative, and no source of infection was found.

Source: Mayo Clinic Proceedings - June 30, 2019 Category: Internal Medicine Authors: Abdullah S. Al Saleh, M. Hasib Sidiqi, Morie A. Gertz Tags: Letter to the Editor Source Type: research