Effects of Bifidobacterium infantis on cytokine-induced neutrophil chemoattractant and insulin-like growth factor-1 in the ileum of rats with endotoxin injury.

CONCLUSION: Expression of CINC mRNA increased in the ileum of preweaning rats with endotoxin injury, and exogenous administration of Bifidobacterium reduced CINC mRNA expression. IGF-1 protein and mRNA expression decreased in the ileum of preweaning rats with endotoxin injury, and exogenous administration of Bifidobacterium prevented the decrease in IGF-1 expression. Bifidobacterium may increase IGF-1 expression and enhance intestinal immune barrier function in rats with endotoxin injury.
PMID: 31249450 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - June 20, 2019 Category: Gastroenterology Authors: Wang W, Sun M, Zheng YL, Sun LY, Qu SQ Tags: World J Gastroenterol Source Type: research