Susceptibility-Guided vs Empiric Therapy for H. pylori Susceptibility-Guided vs Empiric Therapy for H. pylori

How do these treatment strategies for H pylori compare in terms of achieving eradication?Alimentary Pharmacology &Therapeutics
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news

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Existing literature documents an association between Helicobacter pylori (H. pylori) infection and chronic spontaneous urticaria (CSU). However, standard practice for diagnosis and management of CSU does not include testing and treatment of H. pylori. This systematic review aims to assess whether eradication of H. pylori leads to clinical improvement in CSU.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
r A Abstract The gastric bacterium Helicobacter pylori efficiently evades innate immune detection and persistently colonizes its human host. Understanding the genetic determinants that H. pylori uses to establish and maintain persistence, along with their cellular targets, is key to our understanding of the pathogenesis of this extraordinarily successful bacterial colonizer of the human stomach. This review highlights recent advances in elucidating innate immune recognition of H. pylori, its interactions with myeloid cells and the consequences that this very local infection has for immune responses at extragastric...
Source: Current Opinion in Microbiology - Category: Microbiology Authors: Tags: Curr Opin Microbiol Source Type: research
Authors: Zhang L, Lan Y, Wang Q, Zhang Y, Si X Abstract Aim: To evaluate the eradication rate, safety, and compliance of minocycline-containing bismuth quadruple regimens in patients with an untreated Helicobacter pylori (H. pylori) infection. Methods: A total of 360 patients with an untreated H. pylori infection were enrolled in this study between June 2017 and October 2018. Patients were randomly divided into a minocycline/amoxicillin (RMAB) group, a minocycline/metronidazole (RMMB) group, or an amoxicillin/clarithromycin (RACB) group, and all groups received a combined treatment approach with rabeprazole and...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
In the early 1990s, doctors began describing a new condition affecting the esophagus of patients who were predisposed to allergies including food allergy, asthma, and eczema, and who were having trouble swallowing. Today, we call this condition eosinophilic esophagitis (EoE). What is EoE? EoE is an allergic inflammation of the esophagus that causes a range of symptoms. Adolescents and adults most often experience it as difficulty swallowing, sometimes feeling like food moves too slowly through the esophagus and into the stomach. In some cases, food actually gets stuck (and may require urgent removal). Children and some adu...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Allergies Digestive Disorders Health Source Type: blogs
Abstract Chronic urticaria is an uncommon disorder in children but can present considerable morbidity, as well as frustration for the healthcare provider and parent. The prevalence is 0.1-0.3% but can vary considerably by country. Chronic spontaneous urticaria (no identifiable cause) is responsible for 70-80% of chronic urticaria, about half of this due to a subtype called chronic autoimmune urticaria identified by the presence of autoantibodies to IgE or the IgE receptor. Chronic urticaria that is triggered by external physical stimuli is called chronic inducible urticaria and is present in another 15-20%. Allerg...
Source: Paediatric Drugs - Category: Pediatrics Authors: Tags: Paediatr Drugs Source Type: research
Urticaria is characterized by the appearance of hives or angioedema.1 Chronic urticaria is defined by urticarial episodes that last more than 6 weeks, occurring daily or several times per week.2 Although acute urticaria is commonly associated with infections,3 most cases of chronic urticaria have no identifiable cause. Nevertheless, several reports documented chronic urticaria from infectious causes including Helicobacter pylori.4 Studies show association of upper respiratory infections, including sinusitis, with chronic urticaria with remission after antibiotic therapy.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Correspondence Source Type: research
Helicobacter pylori (H.pylori) is a common gastrointestinal infection that typically requires multi-drug therapy for its cure. There are few published case reports on anaphylaxis to proton pump inhibitors (PPIs), a key component to H. pylori therapy. These case reports include patients undergoing treatment for H. pylori. H. pylori has also been associated with chronic urticaria, which can confound the clinical diagnosis of a drug reaction.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
Publication date: Available online 16 August 2019Source: Best Practice &Research Clinical GastroenterologyAuthor(s): Marjorie M. Walker, Michael D. Potter, Nicholas J. TalleyAbstractFunctional dyspepsia (FD) is a common, costly and complex disease, currently defined by symptoms, directed by the Rome consensus on functional bowel disorders, which has evolved over the past two decades. Symptoms include abdominal pain, are often meal related and there are two major subtypes, postprandial distress syndrome and epigastric pain syndrome, not attributed to pathology.Increasingly it is recognised that tangible pathologies occu...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
Abstract CXC Chemokine Ligand 8 (CXCL8) plays an important role in gastric inflammation and in the progression of gastric cancer induced by Helicobacter pylori (H. pylori) infection. The association of CXCL8, CXC Chemokine Receptor 1 (CXCR1), and CXC Chemokine Receptor 2 (CXCR2) polymorphisms with H. pylori infection and gastric cancer progression needs to be investigated in a population within an enigma area consisting of multiple ethnicities, such as Thailand. To analyze the relative risk of H. pylori infection and gastric cancer among Thai gastroduodenal patients, gene polymorphisms in CXCL8 (promoter region -2...
Source: Iranian Journal of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Iran J Allergy Asthma Immunol Source Type: research
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Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Review of Therapeutics Source Type: research
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