Fatal events during clinical trials: an evaluation of deaths during breast cancer studies.
CONCLUSIONS: Death during study treatment was mainly related to infections, and patients with advanced disease, high BMI, underlying comorbidities, CRFs and concomitant medications. If considered for study participation these patients need careful monitoring due to their higher risk for death on study. PMID: 31254201 [PubMed - as supplied by publisher]
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00361A, PaperZhixing Ge, Junhua Zhao, Haibo Yu, Wenguang Yang, Peilin Zhou, Zhenning Wang, Lianqing Liu Currently, the mechanisms underlying the peritoneal metastasis of gastric cancer cells and the function of mesothelial cells during this process are unclear, primarily due to the absence of an effective... The content of this RSS Feed (c) The Royal Society of Chemistry
Chem. Commun., 2020, Advance Article DOI: 10.1039/D0CC03614E, CommunicationWentao Zhang, Hyunjun Choi, Bo Yu, Dong-Hyun Kim Iron oxide nanocube patched Janus magnetic porous silica nanocarriers are synthesized and it is expected to be used for a new type of multifunctional carriers in image guided cancer therapeutic applications. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
NIEHS grantees study pet dogs to better understand how human exposure to everyday chemicals may lead to cancer and other conditions. (read more)
New findings from the Agricultural Health Study suggest exposure to certain pesticides may increase risk of renal cell carcinoma. (read more)
NIEHS and Canadian scientists discover that cancer cells with mutated BRCA1 and BRCA2 genes died when they lacked a protein called APE2. (read more)
Publication date: Available online 5 July 2020Source: Genes &DiseasesAuthor(s): Xi Liu, Jimin Xu, Jia Zhou, Qiang Shen
BACKGROUND: Neighbourhood has risen as a relevant determinant of health. While there is substantial evidence that environmental factors affect health, far less evidence of the role of social mechanisms in the causal chain between neighbourhood characterist...
Publication date: Available online 5 July 2020Source: The American Journal of SurgeryAuthor(s): Brianne J. Sullivan, Natasha L. Leigh, Eliahu Y. Bekhor, Matthew Carpiniello, Daniel Solomon, Deepa R. Magge, Umut Sarpel, Benjamin J. Golas, Daniel M. Labow
The family name of the corresponding author on the original version of this article was incorrectly spelled as “Mariana Philipos”.
CONCLUSION: The proper treatment of pleural effusion can be determined only after meticulous differential diagnosis. The range of therapeutic options has recently become much wider. More data can be expected in the near future concerning diagnostic test- ing for the etiology of the effusion, better pleurodetic agents, the development of interventional techniques, and the genetic background of the affected patients. PMID: 31315808 [PubMed - in process]