Prognostic score and cytogenetic risk classification for chronic lymphocytic leukemia patients: Center for International Blood and Marrow Transplant Research report.

CONCLUSIONS: In this large cohort of previously treated CLL patients who underwent RIC HCT, we developed a robust prognostic scoring system of HCT outcomes and a novel cytogenetic based risk stratification system. These prognostic models can be used for counseling patients, comparing data across studies, and providing a benchmark for future interventions. For future study, we will further validate these models for patients receiving targeted therapies prior to HCT.
PMID: 31253630 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - June 27, 2019 Category: Cancer & Oncology Authors: Kim HT, Ahn KW, Hu ZH, Davids MS, Volpe V, Antin JH, Sorror M, Shadman M, Press OW, Pidala J, Hogan W, Negrin R, Devine S, Uberti J, Agura E, Nash R, Mehta J, McGuirk JP, Forman S, Langston A, Giralt S, Perales MA, Battiwalla M, Hale G, Gale RP, Marks DI, Tags: Clin Cancer Res Source Type: research