Estrogen and estrogen receptor signaling promotes allergic immune responses: Effects on immune cells, cytokines, and inflammatory factors involved in allergy.

Estrogen and estrogen receptor signaling promotes allergic immune responses: Effects on immune cells, cytokines, and inflammatory factors involved in allergy.
Allergol Immunopathol (Madr). 2019 Jun 24;:
Authors: Fan Z, Che H, Yang S, Chen C
Abstract
Hypersensitivity occurs when the body is stimulated by an antigen, resulting in an immune response, and leads to a physiological disorder or abnormal tissue trauma. Various immune cells, cytokines, and inflammatory mediators are involved in the immune responses related to allergic diseases, which are the core of anaphylaxis. Estrogen receptors are widely distributed in immune cells, which combine with estrogen and participate in allergic responses by affecting immune cells, cytokines, and inflammatory factors. We aimed to summarize the association between estrogen and allergic reactions to provide a scientific basis for understanding and studying the mechanisms of allergic diseases.
PMID: 31248582 [PubMed - as supplied by publisher]

Source: Allergologia et Immunopathologia - June 23, 2019 Category: Allergy & Immunology Authors: Fan Z, Che H, Yang S, Chen C Tags: Allergol Immunopathol (Madr) Source Type: research