This study showed the antileishmanial activity of compounds 1 and 2 isolated from N. oppositifolia. Furthermore, compound 2 demonstrated an antileishmanial activity towards amastigotes associated to an immunomodulatory effect.
Conclusions: Proper sample preparation allowed the proteomic and de novo identification of different proteins in the D. melanostictus parotoid macrogland secretion. These results may increase the knowledge about the universe of molecules that compose amphibian skin secretion, as well as to understand their biological/physiological role in the granular gland.
Publication date: Available online 19 August 2019Source: Artificial Intelligence in MedicineAuthor(s): Anders Reenberg Andersen, Wim Vancroonenburg, Greet Vanden BergheAbstractProviding patients with the best possible care is the most essential function of any hospital. In an increasing number of countries, hospitals are governed by the number of patients they are able to attract and the corresponding services they provide for patients. One such service, which is often of significant importance for patients, is the option to choose their room type.Hospital decision makers would benefit from a strategic method for optimizin...
This study found that liver transplant patients are at high risk of developing cardiovascular events post transplantation, even with no pre-existing risk factors. Can predictors be determined?Liver International
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB01686D, CommunicationShiva P Adhikari, Raymond Emehiser, Saswata Karmakar, Patrick J. Hrdlicka Double-stranded oligodeoxyribonucleotides with +1 interstrand zipper arrangements of 2'-O-(pyren-1-yl)methyl-RNA monomers are additionally activated for highly specific recognition of mixed-sequence DNA targets through incorporation of non-nucleotidic spermine bulges. The content of this RSS Feed (c) The Royal Society of Chemistry
Legislators, nonprofit groups and business leaders attended a blessing ceremony for the the new Joint Outreach Center medical clinic in Kaneohe on Friday. The following day, the center held an open house that allowed members of the community to learn more about how the clinic plans to respond to the health care needs of Windward Oahu's homeless population — the second highest number of unsheltered homeless on the Island, according to the Institute for Human Services.
This three-year pilot program…