What is This Itchy Rash?
Discussion Atopic dermatitis (AD) has a prevalence of 3-5% in the overall U.S. population but is increasing with an estimated 10-15% lifetime risk in childhood. It is even more common in children of color with a prevalence in African-American/black children of 17% and Hispanic children of 14%. Health care utilization data also appears to support more severe disease in children of color also. Atopic dermatitis or eczema is a common dermatological skin problem which characteristically is a pruritic, papular eruption with erythema. Like most papulosquamous eruptions it often occurs in intertrigenous areas in people with allergic constitutions or with a family history of atopy. Sometimes atopic dermatitis is described as the “itch that rashes.” Rubbing and scratching can lead to excoriation and, over time, lichenification. There can also be secondary infections or changes to the skin pigmentation (hyper- or hypo-) in affected areas. AD does not have scale which occurs in other papulosquamous eruptions such as psoriasis or tinea. Emollients for skin rehydration are a mainstay of treatment. Topical steroids are commonly used to decrease inflammation in affected areas. Immunosuppressants such as tacrolimus are also used in some cases. Common differential diagnoses include contact dermatitis, keratosis pilaris, nummerular dermatitis, psoriasis, scabies, seborrhea and tinea corporis, but others can also be considered depending on age and circumstances. A more extensive d...
ConclusionOverweight and obesity was higher in males as compared to females, those who were in the upper class and those who were older than 23 years.
CONCLUSION: LSS using three time-point (C1, C4, and C8) provides the most reliable and accurate simultaneous estimation of the AUC0-12 of MPA and AcMPAG in Japanese lung transplant patients. PMID: 31430249 [PubMed - in process]
Although control of chronic glycemia in the population with diabetes and end-stage renal disease (ESRD) has been extensively studied in recent years, the unique problems of short-term glycemic management in acutely ill patients undergoing dialysis have received little attention. Bally et al. evaluated the role of a “closed-loop” (glucose sensor/algorithm tablet device/insulin pump) system in a cohort of hospitalized patients with type 2 diabetes receiving hemodialysis. Compared with usual care, the intervention group had superior glycemic control without increased hypoglycemic events.
A 39-year-old male, live-related renal transplant recipient with stable graft function presented with multiple painless, non-itchy, papular lesions over the midback region. Three months later, these lesions became multiple abscesses with pus exudation (Figure 1). The patient had a history of injury to his midback from the sharp edge of cement stairs, which caused an abrasion. He had received a thymoglobulin induction and was on prednisolone, tacrolimus, and azathioprine. The microscopic examination of KOH mount of pus revealed multiple, septate, branch ing, brown-pigmented hyphae with thick-walled vesicular swellings...
A 41-year-old Congolese woman born in 1977 presented in February 2018 to our emergency department with severe abdominal pain. Her medical history was notable for idiopathic collapsing glomerulopathy for which she was being initially treated with corticosteroids, later switched to tacrolimus. Additionally she was on candesartan 16 mg/d, then later switched in 2014 to enalapril 20 mg/d. During 2017, she was poorly compliant with her medications. In February 2018, her medications included tacrolimus, furosemide, spironolactone, lercanidipine, and enalapril.
An 82-year-old male, with a history of bowel cancer with partial colectomy, gastroesophageal reflux disease, remote partial gastrectomy for peptic ulcer disease, and no documented prior kidney disease, presents with several months of fatigue and subacute decline in kidney function. He had no history of diabetes, hypertension, kidney stones, or prior urinary tract infections. He denied use of nonsteroidal anti-inflammatory agents, herbal medications, and recent antibiotics. There was no family history of renal disease.
This study was performed in order to determine the effect of energy drinks (ED) use on fatigue and sleep disorders in bus drivers. It was planned between April and May 2017 as a descriptive and cross-sectional design. 239 out of the 357 bus drivers who met...
The study explores thoughts, feelings, and beliefs of victims about their experiences of abuse and neglect and how therapeutic intervention encourages disclosure. Narrative accounts given by 15 Indian adolescents during therapeutic interventions were analy...
Authors: Carretero-Anibarro E, Hamud-Uedha M PMID: 31427152 [PubMed - as supplied by publisher]
CONCLUSIONS: Dapagliflozin, in subjects with DM2, produces a medium to long-term decrease in arterial stiffness. PMID: 31420083 [PubMed - as supplied by publisher]
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