Chromone derivatives, R- and S- taeniolin, from the marine-derived fungus Taeniolella sp. BCC31839.

Chromone derivatives, R- and S- taeniolin, from the marine-derived fungus Taeniolella sp. BCC31839. Nat Prod Res. 2019 Jun 28;:1-7 Authors: Intaraudom C, Bunbamrung N, Dramae A, Boonyuen N, Choowong W, Rachtawee P, Pittayakhajonwut P Abstract Two unknown enantiomeric compounds, named (R)- and (S)-taeniolin, along with six known compounds, were isolated from the marine-associated fungus Taeniolella sp. BCC31839. Chemical structures were determined by NMR spectroscopic techniques, and the absolute configurations were confirmed by Mosher application together with CD spectral analyses. Both were inactive for antimicrobial activity against multidrug-resistant malaria parasite (Plasmodium falciparum) and bacteria (Mycobacerium tuberculosis and Bacillus cereus) at maximum tested concentration. PMID: 31250661 [PubMed - as supplied by publisher]
Source: Natural Product Research - Category: Biochemistry Authors: Tags: Nat Prod Res Source Type: research