Identification of rare copy number variations reveals PJA2, APCS, SYNPO, and TAC1 as novel candidate genes in Autism Spectrum Disorders

ConclusionOur study broadens the population spectrum of studied ASD patients and adds new candidates at the list of genes contributing to these disorders.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Many parents have tried putting their autistic children on gluten-free diets, in the hope that it would improve their symptoms. A new study finds that gluten-free diets have no effect on autism.
Source: Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
These frameworks describe the skills, knowledge and behaviours needed by health and social care staff, and will be used to inform the development and planning of the current and future workforce.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
An increasing number of students with autism spectrum disorder (ASD) enroll in inclusive schools and classrooms. The aim of this study was to research how students with ASD experience the social aspect of inclusive high schools. Five adolescences with Aspe...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Translational Psychiatry, Published online: 11 November 2019; doi:10.1038/s41398-019-0641-0Modulation of brain activation during executive functioning in autism with citalopram
Source: Translational Psychiatry - Category: Psychiatry Authors: Source Type: research
This review presents an outline of executive function (EF) and its application to autism spectrum disorder (ASD). The development of the EF construct, theoretical models of EF, and limitations in the study of EF are outlined. The potential of EF as a cognitive endophenotype for ASD is reviewed, and the Research Domain Criteria (RDoC) framework is discussed for researching EF in ASD given the multifaceted factors that influence EF performance. A number of executive-focused cognitive models have been proposed to explain the symptom clusters observed in ASD. Empirical studies suggest a broad impairment in EF, although there i...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
This report outlines the development process, content, and global field-testing strategy of the WHO CST program. The CST program is designed to be feasible, scalable, and adaptable and appropriate for implementation in low-resource settings by nonspecialists. The program was informed by an evidence review utilizing a common elements approach and was developed through extensive stakeholder consultation and an iterative revision process. The program is intended for a global audience and was designed to be adapted to the cultural, socioeconomic, geographic, and resource context in which it is used to ensure that it is compreh...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Autism spectrum disorder (ASD) emerges during early childhood and is marked by a relatively narrow window in which infants transition from exhibiting normative behavioral profiles to displaying the defining features of the ASD phenotype in toddlerhood. Prospective brain imaging studies in infants at high familial risk for autism have revealed important insights into the neurobiology and developmental unfolding of ASD. In this article, we review neuroimaging studies of brain development in ASD from birth through toddlerhood, relate these findings to candidate neurobiological mechanisms, and discuss implications for future r...
Source: Neuroimaging Clinics - Category: Radiology Authors: Source Type: research
Publication date: February 2020Source: Biomedical Signal Processing and Control, Volume 56Author(s): Vida Mehdizadehfar, Farnaz Ghassemi, Ali Fallah, Hamidreza PouretemadAbstractProblems in recognizing facial expressions have been observed in children and adults diagnosed with Autism Spectrum Disorder (ASD) and provided deficits in social interactions. Mild autistic traits have been also detected in first-degree relatives of children with autism, so in this study, difficulty in facial emotion recognition in the fathers of children with autism is investigated using EEG signals. Fifteen biological fathers of children with a ...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
CONCLUSION: The limited availability of services and interventions for individuals with ASD and their families in Seoul in comparison to Massachusetts, underlines target areas for further investment and development. PMID: 31701704 [PubMed - in process]
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research
BACKGROUND: Children are among the most susceptible groups of family violence and this is an important and worrying issue all over the world. Children with disabilities are more vulnerable to family violence. Children with autism are exposed to various typ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
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